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- W4211093154 abstract "Currently used pharmaceutical nanocarriers, such as liposomes, micelles, nanoemulsions, polymeric nanoparticles and many others demonstrate a broad variety of useful properties, such as longevity in the blood allowing for their accumulation in pathological areas with compromised vasculature; specific targeting to certain disease sites due to various targeting ligands attached to the surface of the nanocarriers; enhanced intracellular penetration with the help of surface-attahced cell-penetrating molecules; contrast properties due to the carrier loading with various contrast materials allowing for direct carrier visualization in vivo; stimuli-sensitivity allowing for drug release from the carriers under certain physiological conditions, and others. Some of those pharmaceutical carriers have already made their way into clinic, while others are still under preclinical development. What could be seen much more rare, however, are the pharmaceutical nanocarriers combining several from the listed abilities. Long-circulating immunoliposomes capable of prolonged residence in the blood and specific target recognition represent one of few examples of this kind. At the same time, the enginnering of multifunctional pharmaceutical nanocarriers combinig several useful preoperties in one particle can significantly enhance the efficacy of many therapeutic and diagnostic protocols. This paper considers current status and possible future directions in the emerging area of multifunctional nanocarriers with primary attention on the combination of such properties as longevity, targetability, intracellular penetration and contrast loading." @default.
- W4211093154 created "2022-02-13" @default.
- W4211093154 creator A5084391530 @default.
- W4211093154 date "2012-12-01" @default.
- W4211093154 modified "2023-09-26" @default.
- W4211093154 title "Multifunctional nanocarriers" @default.
- W4211093154 cites W1229041689 @default.
- W4211093154 cites W1278072151 @default.
- W4211093154 cites W1483734912 @default.
- W4211093154 cites W1488249325 @default.
- W4211093154 cites W1495247428 @default.
- W4211093154 cites W1526451509 @default.
- W4211093154 cites W1528820340 @default.
- W4211093154 cites W1549673200 @default.
- W4211093154 cites W1560482245 @default.
- W4211093154 cites W1564872934 @default.
- W4211093154 cites W1574601702 @default.
- W4211093154 cites W1576238436 @default.
- W4211093154 cites W1579604458 @default.
- W4211093154 cites W1584683177 @default.
- W4211093154 cites W1597160917 @default.
- W4211093154 cites W1597997684 @default.
- W4211093154 cites W1767611922 @default.
- W4211093154 cites W1896714280 @default.
- W4211093154 cites W1963819255 @default.
- W4211093154 cites W1965581521 @default.
- W4211093154 cites W1966824444 @default.
- W4211093154 cites W1967228081 @default.
- W4211093154 cites W1968053235 @default.
- W4211093154 cites W1968143647 @default.
- W4211093154 cites W1970019929 @default.
- W4211093154 cites W1970038366 @default.
- W4211093154 cites W1970068648 @default.
- W4211093154 cites W1970168078 @default.
- W4211093154 cites W1970239046 @default.
- W4211093154 cites W1971290197 @default.
- W4211093154 cites W1971762800 @default.
- W4211093154 cites W1972115779 @default.
- W4211093154 cites W1972711580 @default.
- W4211093154 cites W1973232544 @default.
- W4211093154 cites W1973897232 @default.
- W4211093154 cites W1974061482 @default.
- W4211093154 cites W1976822357 @default.
- W4211093154 cites W1977103369 @default.
- W4211093154 cites W1977496576 @default.
- W4211093154 cites W1978843382 @default.
- W4211093154 cites W1979996756 @default.
- W4211093154 cites W1980030500 @default.
- W4211093154 cites W1984307295 @default.
- W4211093154 cites W1984739176 @default.
- W4211093154 cites W1984764362 @default.
- W4211093154 cites W1984987343 @default.
- W4211093154 cites W1985263520 @default.
- W4211093154 cites W1985858988 @default.
- W4211093154 cites W1986020552 @default.
- W4211093154 cites W1986129921 @default.
- W4211093154 cites W1986231975 @default.
- W4211093154 cites W1986264109 @default.
- W4211093154 cites W1986868685 @default.
- W4211093154 cites W1987848642 @default.
- W4211093154 cites W1988217845 @default.
- W4211093154 cites W1989073386 @default.
- W4211093154 cites W1989929454 @default.
- W4211093154 cites W1990946282 @default.
- W4211093154 cites W1991190678 @default.
- W4211093154 cites W1992734626 @default.
- W4211093154 cites W1993834904 @default.
- W4211093154 cites W1994139290 @default.
- W4211093154 cites W1994294376 @default.
- W4211093154 cites W1995305712 @default.
- W4211093154 cites W1995637639 @default.
- W4211093154 cites W1995995697 @default.
- W4211093154 cites W1996295105 @default.
- W4211093154 cites W1998129712 @default.
- W4211093154 cites W1999220393 @default.
- W4211093154 cites W2001101070 @default.
- W4211093154 cites W2001107461 @default.
- W4211093154 cites W2001684619 @default.
- W4211093154 cites W2002516695 @default.
- W4211093154 cites W2003081851 @default.
- W4211093154 cites W2003140922 @default.
- W4211093154 cites W2003326198 @default.
- W4211093154 cites W2004739654 @default.
- W4211093154 cites W2005480600 @default.
- W4211093154 cites W2006982538 @default.
- W4211093154 cites W2008594853 @default.
- W4211093154 cites W2008905120 @default.
- W4211093154 cites W2009038500 @default.
- W4211093154 cites W2009447610 @default.
- W4211093154 cites W2009641790 @default.
- W4211093154 cites W2010506651 @default.
- W4211093154 cites W2010655741 @default.
- W4211093154 cites W2011414490 @default.
- W4211093154 cites W2011525185 @default.
- W4211093154 cites W2011732682 @default.
- W4211093154 cites W2012619372 @default.
- W4211093154 cites W2016049885 @default.
- W4211093154 cites W2018107016 @default.