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- W4211138571 abstract "Pentameric neurotransmitter-gated ion channels, including the serotonin type 3 and nicotinic acetylcholine receptors, have been found to play critical roles in irritable bowel syndrome, mood disorders, rheumatoid arthritis, inflammation, COVID-19, Alzheimer's disease, Parkinson's disease, epilepsy, schizophrenia, and nicotine addiction. They are currently targeted by many clinically used drugs. These drugs convey their effects via allosteric mechanisms or direct channel block due to diverse binding sites for these compounds within the pentameric receptor assemblies." @default.
- W4211138571 created "2022-02-13" @default.
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- W4211138571 date "2022-02-01" @default.
- W4211138571 modified "2023-09-29" @default.
- W4211138571 title "Interaction interface between pentameric neurotransmitter-gated ion channels and RIC-3 chaperone" @default.
- W4211138571 doi "https://doi.org/10.1016/j.bpj.2021.11.1527" @default.
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