Matches in SemOpenAlex for { <https://semopenalex.org/work/W4211156466> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4211156466 endingPage "106807" @default.
- W4211156466 startingPage "106807" @default.
- W4211156466 abstract "Newly discovered evidence showed that long non-coding RNAs (lncRNAs) can play crucial roles in the development of cancer therapies. Nuclear Enriched Abundant Transcripts 1 (NEAT1) is one of the lncRNAs the expression of which changes in different cancers. The role of NEAT1 in apoptosis is discussed in various malignancies. This study aimed to determine the NEAT1 expression and its correlation with P53, PTEN, and BCL-2 genes expression in acute myeloid leukemia (AML) patients.In this study, using quantitative real-time polymerase chain reaction (qRT-PCR), we analyzed the expression of NEAT1, P53, PTEN, and BCL-2 genes in 21 AML patients. Moreover, relative quantification analysis was performed by delta-delta CT method (2 -ΔΔCT) method.Our results showed that NEAT1 expression was significantly lower in AML patients compared to healthy controls (P-value < 0.05). While a significant correlation was observed between the expression levels of NEAT1 and PTEN genes in AML patients (P-value < 0.05), there was no correlation between the expression levels of NEAT1 with P53 and BCL-2 (P-value > 0.05).According to the results, increased expression of NEAT1 gene may play a role in the apoptosis of AML cells, despite the oncogenic role in most solid tumors." @default.
- W4211156466 created "2022-02-13" @default.
- W4211156466 creator A5008704187 @default.
- W4211156466 creator A5058335802 @default.
- W4211156466 creator A5060365549 @default.
- W4211156466 creator A5064399663 @default.
- W4211156466 creator A5085731647 @default.
- W4211156466 creator A5089540127 @default.
- W4211156466 date "2022-04-01" @default.
- W4211156466 modified "2023-09-26" @default.
- W4211156466 title "Altered expression of NEAT1 variants and P53, PTEN, and BCL-2 genes in patients with acute myeloid leukemia" @default.
- W4211156466 cites W2005357616 @default.
- W4211156466 cites W2007520265 @default.
- W4211156466 cites W2035911326 @default.
- W4211156466 cites W2039816251 @default.
- W4211156466 cites W2050237143 @default.
- W4211156466 cites W2057650127 @default.
- W4211156466 cites W2060772907 @default.
- W4211156466 cites W2070777085 @default.
- W4211156466 cites W2077863885 @default.
- W4211156466 cites W2081184407 @default.
- W4211156466 cites W2102423175 @default.
- W4211156466 cites W2115707319 @default.
- W4211156466 cites W2130727876 @default.
- W4211156466 cites W2443106611 @default.
- W4211156466 cites W2558627232 @default.
- W4211156466 cites W2561752776 @default.
- W4211156466 cites W2573692464 @default.
- W4211156466 cites W2892751335 @default.
- W4211156466 cites W2900490748 @default.
- W4211156466 cites W2916911849 @default.
- W4211156466 cites W2959960876 @default.
- W4211156466 cites W3036033661 @default.
- W4211156466 cites W3092392476 @default.
- W4211156466 cites W4312790597 @default.
- W4211156466 doi "https://doi.org/10.1016/j.leukres.2022.106807" @default.
- W4211156466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35231756" @default.
- W4211156466 hasPublicationYear "2022" @default.
- W4211156466 type Work @default.
- W4211156466 citedByCount "5" @default.
- W4211156466 countsByYear W42111564662022 @default.
- W4211156466 countsByYear W42111564662023 @default.
- W4211156466 crossrefType "journal-article" @default.
- W4211156466 hasAuthorship W4211156466A5008704187 @default.
- W4211156466 hasAuthorship W4211156466A5058335802 @default.
- W4211156466 hasAuthorship W4211156466A5060365549 @default.
- W4211156466 hasAuthorship W4211156466A5064399663 @default.
- W4211156466 hasAuthorship W4211156466A5085731647 @default.
- W4211156466 hasAuthorship W4211156466A5089540127 @default.
- W4211156466 hasConcept C104317684 @default.
- W4211156466 hasConcept C121608353 @default.
- W4211156466 hasConcept C150194340 @default.
- W4211156466 hasConcept C190283241 @default.
- W4211156466 hasConcept C203014093 @default.
- W4211156466 hasConcept C2777609662 @default.
- W4211156466 hasConcept C2778461978 @default.
- W4211156466 hasConcept C2778729363 @default.
- W4211156466 hasConcept C2779282312 @default.
- W4211156466 hasConcept C48023723 @default.
- W4211156466 hasConcept C49105822 @default.
- W4211156466 hasConcept C502942594 @default.
- W4211156466 hasConcept C54355233 @default.
- W4211156466 hasConcept C86554907 @default.
- W4211156466 hasConcept C86803240 @default.
- W4211156466 hasConceptScore W4211156466C104317684 @default.
- W4211156466 hasConceptScore W4211156466C121608353 @default.
- W4211156466 hasConceptScore W4211156466C150194340 @default.
- W4211156466 hasConceptScore W4211156466C190283241 @default.
- W4211156466 hasConceptScore W4211156466C203014093 @default.
- W4211156466 hasConceptScore W4211156466C2777609662 @default.
- W4211156466 hasConceptScore W4211156466C2778461978 @default.
- W4211156466 hasConceptScore W4211156466C2778729363 @default.
- W4211156466 hasConceptScore W4211156466C2779282312 @default.
- W4211156466 hasConceptScore W4211156466C48023723 @default.
- W4211156466 hasConceptScore W4211156466C49105822 @default.
- W4211156466 hasConceptScore W4211156466C502942594 @default.
- W4211156466 hasConceptScore W4211156466C54355233 @default.
- W4211156466 hasConceptScore W4211156466C86554907 @default.
- W4211156466 hasConceptScore W4211156466C86803240 @default.
- W4211156466 hasFunder F4320322855 @default.
- W4211156466 hasLocation W42111564661 @default.
- W4211156466 hasLocation W42111564662 @default.
- W4211156466 hasOpenAccess W4211156466 @default.
- W4211156466 hasPrimaryLocation W42111564661 @default.
- W4211156466 hasRelatedWork W1811249054 @default.
- W4211156466 hasRelatedWork W1940364662 @default.
- W4211156466 hasRelatedWork W2109763600 @default.
- W4211156466 hasRelatedWork W2192877027 @default.
- W4211156466 hasRelatedWork W2386662296 @default.
- W4211156466 hasRelatedWork W2792929645 @default.
- W4211156466 hasRelatedWork W2981891990 @default.
- W4211156466 hasRelatedWork W3016920475 @default.
- W4211156466 hasRelatedWork W3024001731 @default.
- W4211156466 hasRelatedWork W4320019111 @default.
- W4211156466 hasVolume "115" @default.
- W4211156466 isParatext "false" @default.
- W4211156466 isRetracted "false" @default.
- W4211156466 workType "article" @default.