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- W4211176076 abstract "The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant variants of SARS-CoV-2 are emerging in due course of time with substantial mutations, having the immune escape property. Simultaneously, the vaccination drive against this virus is in progress worldwide. However, vaccine evasion has been noted by some of the newly emerging variants. Our review provides an overview of the emerging variants' immune escape and vaccine escape ability. We have illustrated a broad view related to viral evolution, variants, and immune escape ability. Subsequently, different immune escape approaches of SARS-CoV-2 have been discussed. Different innate immune escape strategies adopted by the SARS-CoV-2 has been discussed like, IFN-I production dysregulation, cytokines related immune escape, immune escape associated with dendritic cell function and macrophages, natural killer cells and neutrophils related immune escape, PRRs associated immune evasion, and NLRP3 inflammasome associated immune evasion. Simultaneously we have discussed the significant mutations related to emerging variants and immune escape, such as mutations in the RBD region (N439K, L452R, E484K, N501Y, K444R) and other parts (D614G, P681R) of the S-glycoprotein. Mutations in other locations such as NSP1, NSP3, NSP6, ORF3, and ORF8 have also been discussed. Finally, we have illustrated the emerging variants' partial vaccine (BioNTech/Pfizer mRNA/Oxford-AstraZeneca/BBIBP-CorV/ZF2001/Moderna mRNA/Johnson & Johnson vaccine) escape ability. This review will help gain in-depth knowledge related to immune escape, antibody escape, and partial vaccine escape ability of the virus and assist in controlling the current pandemic and prepare for the next." @default.
- W4211176076 created "2022-02-13" @default.
- W4211176076 creator A5001497588 @default.
- W4211176076 creator A5020432140 @default.
- W4211176076 creator A5033972031 @default.
- W4211176076 creator A5056540491 @default.
- W4211176076 date "2022-02-09" @default.
- W4211176076 modified "2023-10-06" @default.
- W4211176076 title "A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations" @default.
- W4211176076 cites W1510501987 @default.
- W4211176076 cites W1548322053 @default.
- W4211176076 cites W1560860164 @default.
- W4211176076 cites W1600560134 @default.
- W4211176076 cites W1812661455 @default.
- W4211176076 cites W1966478716 @default.
- W4211176076 cites W1975272103 @default.
- W4211176076 cites W1976508885 @default.
- W4211176076 cites W1987329700 @default.
- W4211176076 cites W1989893709 @default.
- W4211176076 cites W1991263063 @default.
- W4211176076 cites W1994645566 @default.
- W4211176076 cites W1995744610 @default.
- W4211176076 cites W2005355901 @default.
- W4211176076 cites W2010180575 @default.
- W4211176076 cites W2017167014 @default.
- W4211176076 cites W2017309788 @default.
- W4211176076 cites W2023168923 @default.
- W4211176076 cites W2024444641 @default.
- W4211176076 cites W2024524568 @default.
- W4211176076 cites W2030612634 @default.
- W4211176076 cites W2030917262 @default.
- W4211176076 cites W2036436901 @default.
- W4211176076 cites W2039082139 @default.
- W4211176076 cites W2050107490 @default.
- W4211176076 cites W2052665644 @default.
- W4211176076 cites W2066728093 @default.
- W4211176076 cites W2073300038 @default.
- W4211176076 cites W2078009629 @default.
- W4211176076 cites W2078724846 @default.
- W4211176076 cites W2079534030 @default.
- W4211176076 cites W2100293996 @default.
- W4211176076 cites W2112534911 @default.
- W4211176076 cites W2114216755 @default.
- W4211176076 cites W2122880566 @default.
- W4211176076 cites W2128009173 @default.
- W4211176076 cites W2128085049 @default.
- W4211176076 cites W2131193659 @default.
- W4211176076 cites W2134522277 @default.
- W4211176076 cites W2144852254 @default.
- W4211176076 cites W2145243874 @default.
- W4211176076 cites W2145605402 @default.
- W4211176076 cites W2147233961 @default.
- W4211176076 cites W2147255904 @default.
- W4211176076 cites W2152287937 @default.
- W4211176076 cites W2152842365 @default.
- W4211176076 cites W2153176177 @default.
- W4211176076 cites W2157929105 @default.
- W4211176076 cites W2160358721 @default.
- W4211176076 cites W2163215955 @default.
- W4211176076 cites W2165849880 @default.
- W4211176076 cites W2169199351 @default.
- W4211176076 cites W2267315119 @default.
- W4211176076 cites W2289874335 @default.
- W4211176076 cites W2323018461 @default.
- W4211176076 cites W2337596057 @default.
- W4211176076 cites W2345471773 @default.
- W4211176076 cites W2362686016 @default.
- W4211176076 cites W2409117115 @default.
- W4211176076 cites W2416792725 @default.
- W4211176076 cites W2461540377 @default.
- W4211176076 cites W2566532685 @default.
- W4211176076 cites W2598783947 @default.
- W4211176076 cites W2612411445 @default.
- W4211176076 cites W2745141879 @default.
- W4211176076 cites W2748054558 @default.
- W4211176076 cites W2791607308 @default.
- W4211176076 cites W2800975837 @default.
- W4211176076 cites W2804435636 @default.
- W4211176076 cites W2886400088 @default.
- W4211176076 cites W2886709672 @default.
- W4211176076 cites W2905652667 @default.
- W4211176076 cites W2915839491 @default.
- W4211176076 cites W2921012064 @default.
- W4211176076 cites W2943109925 @default.
- W4211176076 cites W2946011020 @default.
- W4211176076 cites W2950672524 @default.
- W4211176076 cites W2954782052 @default.
- W4211176076 cites W2972282349 @default.
- W4211176076 cites W2983988502 @default.
- W4211176076 cites W3007407747 @default.
- W4211176076 cites W3008090185 @default.
- W4211176076 cites W3008827533 @default.
- W4211176076 cites W3008891488 @default.
- W4211176076 cites W3009314935 @default.
- W4211176076 cites W3009859788 @default.
- W4211176076 cites W3011398105 @default.
- W4211176076 cites W3011508332 @default.
- W4211176076 cites W3013843138 @default.
- W4211176076 cites W3013959692 @default.
- W4211176076 cites W3014003872 @default.