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• W4211181572 startingPage "109" @default.
• W4211181572 abstract "Long COVID refers to the lingering symptoms which persist or appear after the acute illness. The dominant long COVID symptoms in the two years since the pandemic began (2020-2021) have been depression, anxiety, fatigue, concentration and cognitive impairments with few reports of psychosis. Whether other symptoms will appear later on is not yet known. For example, dopamine-dependent movement disorders generally take many years before first symptoms are seen. Post-stroke depression and anxiety may explain many of the early long COVID cases. Hemorrhagic, hypoxic and inflammatory damages of the central nervous system, unresolved systematic inflammation, metabolic impairment, cerebral vascular accidents such as stroke, hypoxia from pulmonary damages and fibrotic changes are among the major causes of long COVID. Glucose metabolic and hypoxic brain issues likely predispose subjects with pre-existing diabetes, cardiovascular or lung problems to long COVID as well. Preliminary data suggest that psychotropic medications may not be a danger but could instead be beneficial in combating COVID-19 infection. The same is true for diabetes medications such as metformin. Thus, a focus on sigma-1 receptor ligands and glucose metabolism is expected to be useful for new drug development as well as the repurposing of current drugs. The reported protective effects of psychotropics and antihistamines against COVID-19, the earlier reports of reduced number of sigma-1 receptors in post-mortem schizophrenic brains, with many antidepressant and antipsychotic drugs being antihistamines with significant affinity for the sigma-1 receptor, support the role of sigma and histamine receptors in neuroinflammation and viral infections. Literature and data in all these areas are accumulating at a fast rate. We reviewed and discussed the relevant and important literature." @default.
• W4211181572 created "2022-02-13" @default.
• W4211181572 creator A5031983651 @default.
• W4211181572 creator A5042385396 @default.
• W4211181572 creator A5047942101 @default.
• W4211181572 date "2022-03-03" @default.
• W4211181572 modified "2023-10-05" @default.
• W4211181572 title "Long COVID, neuropsychiatric disorders, psychotropics, present and future" @default.
• W4211181572 cites W1528671480 @default.
• W4211181572 cites W1575396511 @default.
• W4211181572 cites W1593501931 @default.
• W4211181572 cites W1963613469 @default.
• W4211181572 cites W1966411073 @default.
• W4211181572 cites W1970897378 @default.
• W4211181572 cites W1972323962 @default.
• W4211181572 cites W1975549140 @default.
• W4211181572 cites W1979124919 @default.
• W4211181572 cites W1980489554 @default.
• W4211181572 cites W1984731105 @default.
• W4211181572 cites W1986179217 @default.
• W4211181572 cites W1992763610 @default.
• W4211181572 cites W1994618906 @default.
• W4211181572 cites W1996617753 @default.
• W4211181572 cites W2000941955 @default.
• W4211181572 cites W2007231038 @default.
• W4211181572 cites W2019335338 @default.
• W4211181572 cites W2019485775 @default.
• W4211181572 cites W2020394763 @default.
• W4211181572 cites W2021399955 @default.
• W4211181572 cites W2022641654 @default.
• W4211181572 cites W2024187667 @default.
• W4211181572 cites W2030503642 @default.
• W4211181572 cites W2037024614 @default.
• W4211181572 cites W2039910403 @default.
• W4211181572 cites W2042228468 @default.
• W4211181572 cites W2042569825 @default.
• W4211181572 cites W2043612588 @default.
• W4211181572 cites W2051369986 @default.
• W4211181572 cites W2053469757 @default.
• W4211181572 cites W2065167888 @default.
• W4211181572 cites W2065880637 @default.
• W4211181572 cites W2070485847 @default.
• W4211181572 cites W2072252510 @default.
• W4211181572 cites W2073787944 @default.
• W4211181572 cites W2077259494 @default.
• W4211181572 cites W2078300579 @default.
• W4211181572 cites W2082182063 @default.
• W4211181572 cites W2086844246 @default.
• W4211181572 cites W2091828873 @default.
• W4211181572 cites W2112000315 @default.
• W4211181572 cites W2113902650 @default.
• W4211181572 cites W2126347945 @default.
• W4211181572 cites W2127749802 @default.
• W4211181572 cites W2131087015 @default.
• W4211181572 cites W2137104512 @default.
• W4211181572 cites W2138043907 @default.
• W4211181572 cites W2146199520 @default.
• W4211181572 cites W2163226756 @default.
• W4211181572 cites W2166730447 @default.
• W4211181572 cites W2195212233 @default.
• W4211181572 cites W2215395666 @default.
• W4211181572 cites W2271406622 @default.
• W4211181572 cites W2299896901 @default.
• W4211181572 cites W2323018285 @default.
• W4211181572 cites W2324211060 @default.
• W4211181572 cites W2339641321 @default.
• W4211181572 cites W2403429714 @default.
• W4211181572 cites W246668958 @default.
• W4211181572 cites W2471701648 @default.
• W4211181572 cites W2572710398 @default.
• W4211181572 cites W2595791653 @default.
• W4211181572 cites W2614102372 @default.
• W4211181572 cites W2737356580 @default.
• W4211181572 cites W2755129098 @default.
• W4211181572 cites W2768488673 @default.
• W4211181572 cites W2776129125 @default.
• W4211181572 cites W2782458479 @default.
• W4211181572 cites W2797431083 @default.
• W4211181572 cites W2891999707 @default.
• W4211181572 cites W2895936122 @default.
• W4211181572 cites W2907122372 @default.
• W4211181572 cites W2908572629 @default.
• W4211181572 cites W2910607342 @default.
• W4211181572 cites W2914443670 @default.
• W4211181572 cites W2914664753 @default.
• W4211181572 cites W2921715866 @default.
• W4211181572 cites W2950041915 @default.
• W4211181572 cites W2971267227 @default.
• W4211181572 cites W2989514128 @default.
• W4211181572 cites W2999197468 @default.
• W4211181572 cites W3006317414 @default.
• W4211181572 cites W3007147172 @default.
• W4211181572 cites W3007643904 @default.
• W4211181572 cites W3008394341 @default.
• W4211181572 cites W3011537081 @default.
• W4211181572 cites W3011995143 @default.
• W4211181572 cites W3012172004 @default.
• W4211181572 cites W3014186323 @default.

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