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- W4211191704 abstract "Although reef-building corals are declining worldwide, responses to bleaching vary within and across species and are partly heritable. Toward predicting bleaching response from genomic data, we generated a chromosome-scale genome assembly for the coral Acropora millepora We obtained whole-genome sequences for 237 phenotyped samples collected at 12 reefs along the Great Barrier Reef, among which we inferred little population structure. Scanning the genome for evidence of local adaptation, we detected signatures of long-term balancing selection in the heat-shock co-chaperone sacsin We conducted a genome-wide association study of visual bleaching score for 213 samples, incorporating the polygenic score derived from it into a predictive model for bleaching in the wild. These results set the stage for genomics-based approaches in conservation strategies.Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. PMID: 32675347 Funding information This work was supported by: NCRR NIH HHS, United States Grant ID: G20 RR030893" @default.
- W4211191704 created "2022-02-13" @default.
- W4211191704 creator A5013744749 @default.
- W4211191704 creator A5064642955 @default.
- W4211191704 date "2020-10-22" @default.
- W4211191704 modified "2023-09-26" @default.
- W4211191704 title "Faculty Opinions recommendation of Population genetics of the coral Acropora millepora: Toward genomic prediction of bleaching." @default.
- W4211191704 doi "https://doi.org/10.3410/f.738341995.793579611" @default.
- W4211191704 hasPublicationYear "2020" @default.
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