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• W4211210816 endingPage "3181" @default.
• W4211210816 startingPage "3173" @default.
• W4211210816 abstract "S-Nitrosoglutathione (GSNO) is the S-nitrosated derivative of glutathione and is thought to be a critical mediator of the down stream signaling effects of nitric oxide (NO). GSNO has also been implicated as a contributor to various disease states.This review focuses on the chemical nature of GSNO, its biological activities, the evidence that it is an endogenous mediator of NO action, and implications for therapeutic use.GSNO clearly exerts its cellular actions through both NO- and S-nitrosation-dependent mechanisms; however, the chemical and biological aspects of this compound should be placed in the context of S-nitrosation as a whole.GSNO is a central intermediate in formation and degradation of cellular S-nitrosothiols with potential therapeutic applications; thus, it remains an important molecule of study. This article is part of a Special Issue entitled Cellular functions of glutathione." @default.
• W4211210816 created "2022-02-13" @default.
• W4211210816 creator A5022701771 @default.
• W4211210816 creator A5044005348 @default.
• W4211210816 creator A5077857077 @default.
• W4211210816 date "2013-05-01" @default.
• W4211210816 modified "2023-10-14" @default.
• W4211210816 title "S-Nitrosoglutathione" @default.
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