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- W4211218582 abstract "The cross-bridging events within the Lymn-Taylor cycle of cardiac muscle are important regulation steps for the thick filament. The two main conformational changes which “bookend” this process, the adenosine triphosphate (ATP) binding induced changes to the rigor myosin-thin filament complex and the rebinding of pre-power stroke (PPS) myosin to the thin filament, occur at timescales rapid enough to prevent experimental determination, but also at those too long for all atom computational simulations that are generally limited to the femtosecond (fs) to nanosecond (ns) timescales." @default.
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- W4211218582 date "2022-02-01" @default.
- W4211218582 modified "2023-10-14" @default.
- W4211218582 title "Utilization of coarse grained modeling to determine structural changes within cardiac cross-bridging events" @default.
- W4211218582 doi "https://doi.org/10.1016/j.bpj.2021.11.1447" @default.
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