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• W4211219033 startingPage "1" @default.
• W4211219033 abstract "Overview Malignant pleural mesothelioma is an aggressive malignancy with an incidence that may be peaking worldwide in the next 5–10 years. While the majority of patients do ultimately die of this disease, there have been substantial treatment and diagnostic shifts over the past decade that may improve long‐term outcomes. These changes include worldwide interest in defining early detection biomarkers for the disease, a debate as to the optimal surgical approach (extrapleural pneumonectomy vs lung‐sparing methods such as pleurectomy/decortication), further refinement of radiation techniques that allow for conformal treatment fields and the delivery of radiation with the involved lung intact, and the emergence of systemic therapies that are targeted in nature and allow for the increased individualization of care. Indeed, prospective clinical trials assessing the safety and efficacy of novel treatment approaches will be essential to the standardization of paradigms that improve the outcomes. It is hoped that the maturation of these efforts will lead to an optimal approach in which earlier‐stage patients will benefit from multiple modalities that will provide synergistic control while limiting toxicity, thereby increasing the number of long‐term survivors over the next one to two decades." @default.
• W4211219033 created "2022-02-13" @default.
• W4211219033 creator A5055965589 @default.
• W4211219033 creator A5057281549 @default.
• W4211219033 creator A5083444789 @default.
• W4211219033 creator A5091299701 @default.
• W4211219033 date "2017-02-26" @default.
• W4211219033 modified "2023-09-30" @default.
• W4211219033 title "Malignant Pleural Mesothelioma" @default.
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