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- W4211241907 endingPage "402" @default.
- W4211241907 startingPage "379" @default.
- W4211241907 abstract "It is well known that alcoholism is a chronic relapsing illness. While stress significantly impacts alcoholism risk, there is also evidence that increasing levels of alcohol use affect peripheral and central stress and reward pathways thereby setting up a reciprocal relationship among the effects of alcohol consumption of the development, course of and recovery from alcoholism. This chapter reviews our efforts in assessing the integrity of stress pathways in alcoholism by examining whether altered responses of the stress pathways play a role in relapse risk. Using validated human laboratory procedures to model two of the most common situations that contribute to relapse risk, we review how such models in the laboratory can predict subsequent alcohol relapse. Empirical findings from human laboratory and brain imaging studies are reviewed to show that specific stress-related dysregulation accompanies the alcohol craving state in alcohol-dependent individuals, and such dysregulation along with increases in alcohol seeking are predictive of increased alcohol relapse risk. Finally, the significant implications of these findings for the development of novel treatment interventions that target stress processes and alcohol craving to improve alcoholism relapse outcomes are discussed." @default.
- W4211241907 created "2022-02-13" @default.
- W4211241907 creator A5065684362 @default.
- W4211241907 date "2011-01-01" @default.
- W4211241907 modified "2023-10-14" @default.
- W4211241907 title "Modeling Relapse Situations in the Human Laboratory" @default.
- W4211241907 cites W1516025158 @default.
- W4211241907 cites W1573574485 @default.
- W4211241907 cites W1743814207 @default.
- W4211241907 cites W1969528791 @default.
- W4211241907 cites W1970452940 @default.
- W4211241907 cites W1971189295 @default.
- W4211241907 cites W1971449933 @default.
- W4211241907 cites W1975511434 @default.
- W4211241907 cites W1975799116 @default.
- W4211241907 cites W1977027217 @default.
- W4211241907 cites W1977039030 @default.
- W4211241907 cites W1978266818 @default.
- W4211241907 cites W1981424477 @default.
- W4211241907 cites W1981513725 @default.
- W4211241907 cites W1984346427 @default.
- W4211241907 cites W1986331833 @default.
- W4211241907 cites W1986364137 @default.
- W4211241907 cites W1988132969 @default.
- W4211241907 cites W1988922574 @default.
- W4211241907 cites W1992491673 @default.
- W4211241907 cites W1993017526 @default.
- W4211241907 cites W1994122158 @default.
- W4211241907 cites W1994371722 @default.
- W4211241907 cites W1996581174 @default.
- W4211241907 cites W1998826260 @default.
- W4211241907 cites W1999948756 @default.
- W4211241907 cites W2001217292 @default.
- W4211241907 cites W2006116437 @default.
- W4211241907 cites W2007119174 @default.
- W4211241907 cites W2010733076 @default.
- W4211241907 cites W2012417658 @default.
- W4211241907 cites W2018650416 @default.
- W4211241907 cites W2019401805 @default.
- W4211241907 cites W2021125420 @default.
- W4211241907 cites W2022235619 @default.
- W4211241907 cites W2023158239 @default.
- W4211241907 cites W2023308812 @default.
- W4211241907 cites W2024921294 @default.
- W4211241907 cites W2030825740 @default.
- W4211241907 cites W2032197162 @default.
- W4211241907 cites W2034354169 @default.
- W4211241907 cites W2037046817 @default.
- W4211241907 cites W2040903782 @default.
- W4211241907 cites W2043208298 @default.
- W4211241907 cites W2043559838 @default.
- W4211241907 cites W2043621158 @default.
- W4211241907 cites W2044730465 @default.
- W4211241907 cites W2045184489 @default.
- W4211241907 cites W2045368329 @default.
- W4211241907 cites W2045572233 @default.
- W4211241907 cites W2053837680 @default.
- W4211241907 cites W2054971111 @default.
- W4211241907 cites W2057235410 @default.
- W4211241907 cites W2057808550 @default.
- W4211241907 cites W2059944696 @default.
- W4211241907 cites W2061939000 @default.
- W4211241907 cites W2063165584 @default.
- W4211241907 cites W2063556613 @default.
- W4211241907 cites W2064204417 @default.
- W4211241907 cites W2065577847 @default.
- W4211241907 cites W2067431776 @default.
- W4211241907 cites W2069444801 @default.
- W4211241907 cites W2071693918 @default.
- W4211241907 cites W2075114927 @default.
- W4211241907 cites W2083827404 @default.
- W4211241907 cites W2086265757 @default.
- W4211241907 cites W2086805043 @default.
- W4211241907 cites W2087314028 @default.
- W4211241907 cites W2088205856 @default.
- W4211241907 cites W2088355418 @default.
- W4211241907 cites W2091769432 @default.
- W4211241907 cites W2092814050 @default.
- W4211241907 cites W2098642412 @default.
- W4211241907 cites W2103424075 @default.
- W4211241907 cites W2105130852 @default.
- W4211241907 cites W2106719141 @default.
- W4211241907 cites W2106862702 @default.
- W4211241907 cites W2108261924 @default.
- W4211241907 cites W2111751702 @default.
- W4211241907 cites W2113753462 @default.
- W4211241907 cites W2116882701 @default.
- W4211241907 cites W2116965419 @default.
- W4211241907 cites W2121548568 @default.
- W4211241907 cites W2125591713 @default.
- W4211241907 cites W2126189142 @default.
- W4211241907 cites W2126502833 @default.
- W4211241907 cites W2128086091 @default.
- W4211241907 cites W2130114096 @default.
- W4211241907 cites W2130358139 @default.
- W4211241907 cites W2131350997 @default.
- W4211241907 cites W2131510747 @default.
- W4211241907 cites W2133466515 @default.