FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4212775035> ?p ?o ?g. }

• W4212775035 endingPage "415" @default.
• W4212775035 startingPage "396" @default.
• W4212775035 abstract "Since the release of the first global hepatitis elimination targets in 2016, and until the COVID-19 pandemic started in early 2020, many countries and territories were making progress toward hepatitis C virus (HCV) elimination. This study aims to evaluate HCV burden in 2020, and forecast HCV burden by 2030 given current trends.This analysis includes a literature review, Delphi process, and mathematical modelling to estimate HCV prevalence (viraemic infection, defined as HCV RNA-positive cases) and the cascade of care among people of all ages (age ≥0 years from birth) for the period between Jan 1, 2015, and Dec 31, 2030. Epidemiological data were collected from published sources and grey literature (including government reports and personal communications) and were validated among country and territory experts. A Markov model was used to forecast disease burden and cascade of care from 1950 to 2050 for countries and territories with data. Model outcomes were extracted from 2015 to 2030 to calculate population-weighted regional averages, which were used for countries or territories without data. Regional and global estimates of HCV prevalence, cascade of care, and disease burden were calculated based on 235 countries and territories.Models were built for 110 countries or territories: 83 were approved by local experts and 27 were based on published data alone. Using data from these models, plus population-weighted regional averages for countries and territories without models (n=125), we estimated a global prevalence of viraemic HCV infection of 0·7% (95% UI 0·7-0·9), corresponding to 56·8 million (95% UI 55·2-67·8) infections, on Jan 1, 2020. This number represents a decrease of 6·8 million viraemic infections from a 2015 (beginning of year) prevalence estimate of 63·6 million (61·8-75·8) infections (0·9% [0·8-1·0] prevalence). By the end of 2020, an estimated 12·9 million (12·5-15·4) people were living with a diagnosed viraemic infection. In 2020, an estimated 641 000 (623 000-765 000) patients initiated treatment.At the beginning of 2020, there were an estimated 56·8 million viraemic HCV infections globally. Although this number represents a decrease from 2015, our forecasts suggest we are not currently on track to achieve global elimination targets by 2030. As countries recover from COVID-19, these findings can help refocus efforts aimed at HCV elimination.John C Martin Foundation, Gilead Sciences, AbbVie, ZeShan Foundation, and The Hepatitis Fund." @default.
• W4212775035 created "2022-02-24" @default.
• W4212775035 creator A5001376175 @default.
• W4212775035 creator A5001514580 @default.
• W4212775035 creator A5001595357 @default.
• W4212775035 creator A5002031373 @default.
• W4212775035 creator A5002341220 @default.
• W4212775035 creator A5002877545 @default.
• W4212775035 creator A5003049761 @default.
• W4212775035 creator A5003201899 @default.
• W4212775035 creator A5003709175 @default.
• W4212775035 creator A5003813221 @default.
• W4212775035 creator A5004762904 @default.
• W4212775035 creator A5004848036 @default.
• W4212775035 creator A5005099163 @default.
• W4212775035 creator A5005123985 @default.
• W4212775035 creator A5005870196 @default.
• W4212775035 creator A5005960437 @default.
• W4212775035 creator A5007361658 @default.
• W4212775035 creator A5007518376 @default.
• W4212775035 creator A5008698250 @default.
• W4212775035 creator A5009171869 @default.
• W4212775035 creator A5009270009 @default.
• W4212775035 creator A5009520658 @default.
• W4212775035 creator A5009631266 @default.
• W4212775035 creator A5010280579 @default.
• W4212775035 creator A5010694834 @default.
• W4212775035 creator A5010785476 @default.
• W4212775035 creator A5010851202 @default.
• W4212775035 creator A5011362289 @default.
• W4212775035 creator A5011520858 @default.
• W4212775035 creator A5012219931 @default.
• W4212775035 creator A5012559656 @default.
• W4212775035 creator A5012919389 @default.
• W4212775035 creator A5013176250 @default.
• W4212775035 creator A5013729992 @default.
• W4212775035 creator A5014820923 @default.
• W4212775035 creator A5015332236 @default.
• W4212775035 creator A5016042866 @default.
• W4212775035 creator A5016676149 @default.
• W4212775035 creator A5017213091 @default.
• W4212775035 creator A5017525133 @default.
• W4212775035 creator A5018599554 @default.
• W4212775035 creator A5019470247 @default.
• W4212775035 creator A5019602067 @default.
• W4212775035 creator A5019927380 @default.
• W4212775035 creator A5020008026 @default.
• W4212775035 creator A5020345166 @default.
• W4212775035 creator A5021496172 @default.
• W4212775035 creator A5021516311 @default.
• W4212775035 creator A5023245595 @default.
• W4212775035 creator A5023805196 @default.
• W4212775035 creator A5024039879 @default.
• W4212775035 creator A5024581579 @default.
• W4212775035 creator A5024817854 @default.
• W4212775035 creator A5025294986 @default.
• W4212775035 creator A5025315719 @default.
• W4212775035 creator A5026171398 @default.
• W4212775035 creator A5026722725 @default.
• W4212775035 creator A5026730867 @default.
• W4212775035 creator A5026740194 @default.
• W4212775035 creator A5027739167 @default.
• W4212775035 creator A5028553992 @default.
• W4212775035 creator A5028623898 @default.
• W4212775035 creator A5028677580 @default.
• W4212775035 creator A5028736214 @default.
• W4212775035 creator A5029029786 @default.
• W4212775035 creator A5029171591 @default.
• W4212775035 creator A5029743712 @default.
• W4212775035 creator A5030105607 @default.
• W4212775035 creator A5030505658 @default.
• W4212775035 creator A5030887348 @default.
• W4212775035 creator A5030982584 @default.
• W4212775035 creator A5031850543 @default.
• W4212775035 creator A5031867546 @default.
• W4212775035 creator A5032472868 @default.
• W4212775035 creator A5033094895 @default.
• W4212775035 creator A5033678590 @default.
• W4212775035 creator A5033835093 @default.
• W4212775035 creator A5034269872 @default.
• W4212775035 creator A5034416451 @default.
• W4212775035 creator A5034642660 @default.
• W4212775035 creator A5036101648 @default.
• W4212775035 creator A5037581187 @default.
• W4212775035 creator A5037585954 @default.
• W4212775035 creator A5037815003 @default.
• W4212775035 creator A5037869618 @default.
• W4212775035 creator A5037906942 @default.
• W4212775035 creator A5038008674 @default.
• W4212775035 creator A5038410273 @default.
• W4212775035 creator A5038898216 @default.
• W4212775035 creator A5038973448 @default.
• W4212775035 creator A5039554365 @default.
• W4212775035 creator A5040183955 @default.
• W4212775035 creator A5040277974 @default.
• W4212775035 creator A5040857444 @default.
• W4212775035 creator A5041300993 @default.
• W4212775035 creator A5041450939 @default.

• next