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- W4212826776 abstract "In the group of vesiculobullous dermatoses, blistering is the major clinical feature, which results from genetically determined or autoimmune loss of basic structural elements in the skin that maintain cohesion between keratinocytes or between the epidermal layer and the dermis within the basement membrane zone. The majority of vesiculobullous dermatoses are acquired organ-specific autoimmune diseases in which the autoantibodies target structural proteins in the skin, and their diagnosis relies on the application of specialized immunopathology techniques that reveal the presence of in vivo deposited or circulating autoantibodies against various structural proteins. The various subtypes of hereditary EB have varying prognoses based on the mode of transmission and a combination of phenotypic, immunofluorescence, ultrastructural, and molecular findings. Disorders in the group of EB represent a spectrum of blistering and scarring conditions that range from being mild with some inconvenience to life-threatening." @default.
- W4212826776 created "2022-02-24" @default.
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- W4212826776 date "2022-02-23" @default.
- W4212826776 modified "2023-10-16" @default.
- W4212826776 title "Vesiculobullous Diseases" @default.
- W4212826776 doi "https://doi.org/10.1201/9781003105268-14" @default.
- W4212826776 hasPublicationYear "2022" @default.
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