Matches in SemOpenAlex for { <https://semopenalex.org/work/W4212843845> ?p ?o ?g. }
- W4212843845 endingPage "720" @default.
- W4212843845 startingPage "720" @default.
- W4212843845 abstract "Surgical resection remains the first line treatment for salivary gland cancer (SGC). In the case of locally advanced disease, surgery is followed by adjuvant radiotherapy. Surgical resection should be favored in resectable locoregional recurrent disease as well, and even the complete resection of all distant oligometastases has clinical benefit for the patients. For inoperable and disseminated metastatic disease, a multitude of systemic therapies including chemotherapy, targeted therapy, and immunotherapy are available. In this review, the current therapeutic options for inoperable recurrent or metastatic SGCs are summarized. Systemic treatment can achieve prolonged progression-free and overall survival, while the overall prognosis remains poor. Current clinical trials include only a limited number of patients and mostly combine different histologic subtypes. Additionally, no randomized controlled trial comparing different therapeutic options has been performed. In the future, further studies with a larger patient cohort and ideally only one histologic subtype are needed in order to improve the outcome for SGC patients. However, this may be difficult to accomplish due to the rarity and diversity of the disease. Additionally, molecular analyses need to be performed routinely in order to individualize treatment and to go one step further towards precision medicine." @default.
- W4212843845 created "2022-02-24" @default.
- W4212843845 creator A5014096214 @default.
- W4212843845 creator A5024236651 @default.
- W4212843845 creator A5027231637 @default.
- W4212843845 creator A5029592533 @default.
- W4212843845 creator A5032251994 @default.
- W4212843845 creator A5040014533 @default.
- W4212843845 creator A5053999765 @default.
- W4212843845 creator A5062794187 @default.
- W4212843845 creator A5067749722 @default.
- W4212843845 date "2022-01-29" @default.
- W4212843845 modified "2023-10-10" @default.
- W4212843845 title "Targeted Therapy, Chemotherapy, Immunotherapy and Novel Treatment Options for Different Subtypes of Salivary Gland Cancer" @default.
- W4212843845 cites W112388040 @default.
- W4212843845 cites W1495629113 @default.
- W4212843845 cites W1560364460 @default.
- W4212843845 cites W1838206777 @default.
- W4212843845 cites W1872103658 @default.
- W4212843845 cites W1980992166 @default.
- W4212843845 cites W1992894543 @default.
- W4212843845 cites W2010018076 @default.
- W4212843845 cites W2011420636 @default.
- W4212843845 cites W2017035167 @default.
- W4212843845 cites W2032535154 @default.
- W4212843845 cites W2032738666 @default.
- W4212843845 cites W2036589190 @default.
- W4212843845 cites W2048648869 @default.
- W4212843845 cites W2049325430 @default.
- W4212843845 cites W2060525726 @default.
- W4212843845 cites W2061006759 @default.
- W4212843845 cites W2068087217 @default.
- W4212843845 cites W2070165953 @default.
- W4212843845 cites W2077745888 @default.
- W4212843845 cites W2086364834 @default.
- W4212843845 cites W2098523473 @default.
- W4212843845 cites W2098637454 @default.
- W4212843845 cites W2098641060 @default.
- W4212843845 cites W2107071331 @default.
- W4212843845 cites W2107876629 @default.
- W4212843845 cites W2118510514 @default.
- W4212843845 cites W2127917633 @default.
- W4212843845 cites W2128512366 @default.
- W4212843845 cites W2129307197 @default.
- W4212843845 cites W2137228442 @default.
- W4212843845 cites W2141471081 @default.
- W4212843845 cites W2144909477 @default.
- W4212843845 cites W2155961584 @default.
- W4212843845 cites W2162386682 @default.
- W4212843845 cites W2170241131 @default.
- W4212843845 cites W2178274441 @default.
- W4212843845 cites W2185318137 @default.
- W4212843845 cites W2211975754 @default.
- W4212843845 cites W2268032794 @default.
- W4212843845 cites W2290704823 @default.
- W4212843845 cites W2291746651 @default.
- W4212843845 cites W2306233388 @default.
- W4212843845 cites W2320887555 @default.
- W4212843845 cites W2324570764 @default.
- W4212843845 cites W2325489602 @default.
- W4212843845 cites W2343095226 @default.
- W4212843845 cites W2462865110 @default.
- W4212843845 cites W2509315795 @default.
- W4212843845 cites W2546190135 @default.
- W4212843845 cites W2548897214 @default.
- W4212843845 cites W2553335953 @default.
- W4212843845 cites W2565229076 @default.
- W4212843845 cites W2574609272 @default.
- W4212843845 cites W2586843900 @default.
- W4212843845 cites W2586874799 @default.
- W4212843845 cites W2593119424 @default.
- W4212843845 cites W2596539906 @default.
- W4212843845 cites W2605068311 @default.
- W4212843845 cites W2747997276 @default.
- W4212843845 cites W2758417871 @default.
- W4212843845 cites W2765923527 @default.
- W4212843845 cites W2766106171 @default.
- W4212843845 cites W2766313151 @default.
- W4212843845 cites W2775239209 @default.
- W4212843845 cites W2775901338 @default.
- W4212843845 cites W2791074024 @default.
- W4212843845 cites W2792603138 @default.
- W4212843845 cites W2802496767 @default.
- W4212843845 cites W2808967997 @default.
- W4212843845 cites W2837141699 @default.
- W4212843845 cites W2885034079 @default.
- W4212843845 cites W2891215090 @default.
- W4212843845 cites W2901565128 @default.
- W4212843845 cites W2908888879 @default.
- W4212843845 cites W2908917339 @default.
- W4212843845 cites W2944888925 @default.
- W4212843845 cites W2945915849 @default.
- W4212843845 cites W2947440683 @default.
- W4212843845 cites W2965862978 @default.
- W4212843845 cites W2993951052 @default.
- W4212843845 cites W3000605689 @default.
- W4212843845 cites W3003270145 @default.
- W4212843845 cites W3005380219 @default.