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- W4212875212 abstract "The mutation e1662 is an allele of the Caenorhabditis elegans unc-54 gene induced with the difunctional alkylating agent 1,2,7,8-diepoxyoctane. unc-54 encodes the major myosin heavy chain isozyme of body wall muscle cells. Filter-transfer hybridization and DNA sequence analysis show that e1662 is an insertion of 288 base pairs of DNA within unc-54. The inserted DNA is identical to a 288-base pair region of unc-54 located ca. 600 base pairs from the insertion site. Thus, e1662 is a displaced duplication. A 14-base pair sequence located at one end of the duplicated segment is found adjacent to the site of insertion. These homologous sequences are juxtaposed head-to-tail by the insertion event. e1662 thus contains a tandem direct repeat extending across one of its junctions." @default.
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- W4212875212 date "1985-01-01" @default.
- W4212875212 modified "2023-09-26" @default.
- W4212875212 title "Novel insertion mutation in Caenorhabditis elegans." @default.
- W4212875212 doi "https://doi.org/10.1128/mcb.5.1.1" @default.
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