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- W4212881567 abstract "Distant soft-tissue metastases (subcutaneous tissues and skeletal muscle) are extremely rare, specially in esophageal carcinoma. We describe a patient who was treated for oesophageal adenocarcinoma 2.5 years before. A PET/CT was performed showing metastatic spread because of a solitary focus of increased tracer uptake corresponding one subcutaneous node in the upper abdomen. An excisional biopsy proved to be a metastasis from the carcinoma. Restaging 18F-FDG PET/CT study was performed 2 years later demonstrating some focus of increased uptake within several muscles as isolated distant hematogenous spread of metastases, as they were histopathologically confirmed.As most of soft-tissue metastases are asymptomatic, the physicians should recommend histopathological study of focus of FDG uptake at subcutaneous tissues and/or skeletal muscles, because they may be the first sign of disease expansion so therapeutic management of these patients could be changed.Las metástasis en partes blandas (tejido celular subcutáneo y músculo esquelético) son extremadamente raras, especialmente en cáncer de esófago. Presentamos un varón con antecedente de adenocarcinoma de esófago tratado 2,5 años antes, con hallazgo en 18F-FDG PET/TC de afectación metastásica a distancia exclusiva en un nódulo subcutáneo en pared abdominal, con confirmación anatomopatológica tras su resección. En nuevo PET-TAC 18F-FDG realizado 2 años después se objetivó nueva afectación a distancia pero exclusiva en musculatura esquelética, también confirmada histológicamente.Como las lesiones en partes blandas frecuentemente son asintomáticas, ante el hallazgo en un estudio PET de lesiones subcutáneas y/o musculares hipermetabólicas debemos recomendar su estudio histológico, ya que pueden tratarse del primer signo de una metastatización a distancia cambiando radicalmente el manejo terapéutico del paciente." @default.
- W4212881567 created "2022-02-24" @default.
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- W4212881567 date "2021-11-01" @default.
- W4212881567 modified "2023-09-26" @default.
- W4212881567 title "Role of vascular function in early detection of posttraumatic stress disorder, and monitoring response to trauma-informed interventions" @default.
- W4212881567 doi "https://doi.org/10.1016/j.bbi.2021.08.011" @default.
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