Matches in SemOpenAlex for { <https://semopenalex.org/work/W4212913636> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4212913636 endingPage "44" @default.
- W4212913636 startingPage "44" @default.
- W4212913636 abstract "Hepatitis C virus (HCV) genotypes are diverse geographically. Infectivity, pathogenicity, and sustained response to treatment may be influenced by HCV genotypes/subtypes. This study examined the relative distribution of hepatitis C genotypes and subtypes among isolates from 84 individuals with chronic active hepatitis (CAH), 39 haemodialysis patients, and 31 intravenous drug addicts, of Saudi Arabian origin. Reverse transcription-polymerase chain reaction (RT-PCR) using specific primers from the 5′-UTR was performed and amplified products were genotyped/subtyped using a commercial reverse phase hybridisation technique (Innolipa HCV 11, Innogenetics, Belgium). Seventy-four percent of the CAH patients were found to be genotype 4 (4c/4d: 33%; 4h: 14%; 4e: 7%; 4: 20%) but other subtypes such as 1b: 14%, 2b: 4%, 3a: 5%, 5a: 1%, and 6a: 1%, were also detected. A history of blood transfusion was disclosed in only 10% of the CAH group. The pattern among haemodialysis patients was as follows: genotype 4: 49% (4h: 13%; 4: 36% ); 1a: 33%, 1: 3%; 1b: 10%; and 5a: 5%. The intravenous drug addict group showed 39% subtype 1b, but other subtypes such as 9% for 1a; 3% for 2a; 36% for 4; 3% for 5a; and 9% for 3a were seen. It is concluded that genotype 4 is predominant among our HCV isolates from CAH patients but subtype 1a and 1b have emerged among our haemodialysis and intravenous drug addict cases, respectively. A significant relationship between the viral genotype and the source of infection has emerged among Saudi groups at high risk for hepatitis C virus. J. Med. Virol. 58:44–48, 1999. © 1999 Wiley-Liss, Inc." @default.
- W4212913636 created "2022-02-24" @default.
- W4212913636 creator A5017531793 @default.
- W4212913636 creator A5037756966 @default.
- W4212913636 creator A5045351045 @default.
- W4212913636 creator A5053982465 @default.
- W4212913636 creator A5084090002 @default.
- W4212913636 date "1999-05-01" @default.
- W4212913636 modified "2023-10-14" @default.
- W4212913636 title "Hepatitis C genotypes and subtypes in Saudi Arabia" @default.
- W4212913636 doi "https://doi.org/10.1002/(sici)1096-9071(199905)58:1<44::aid-jmv6>3.3.co;2-l" @default.
- W4212913636 hasPublicationYear "1999" @default.
- W4212913636 type Work @default.
- W4212913636 citedByCount "4" @default.
- W4212913636 crossrefType "journal-article" @default.
- W4212913636 hasAuthorship W4212913636A5017531793 @default.
- W4212913636 hasAuthorship W4212913636A5037756966 @default.
- W4212913636 hasAuthorship W4212913636A5045351045 @default.
- W4212913636 hasAuthorship W4212913636A5053982465 @default.
- W4212913636 hasAuthorship W4212913636A5084090002 @default.
- W4212913636 hasConcept C104317684 @default.
- W4212913636 hasConcept C106358424 @default.
- W4212913636 hasConcept C135763542 @default.
- W4212913636 hasConcept C156719811 @default.
- W4212913636 hasConcept C159047783 @default.
- W4212913636 hasConcept C203014093 @default.
- W4212913636 hasConcept C2522874641 @default.
- W4212913636 hasConcept C2776029263 @default.
- W4212913636 hasConcept C2776408679 @default.
- W4212913636 hasConcept C2776455275 @default.
- W4212913636 hasConcept C2780727368 @default.
- W4212913636 hasConcept C2781463415 @default.
- W4212913636 hasConcept C49105822 @default.
- W4212913636 hasConcept C54355233 @default.
- W4212913636 hasConcept C71924100 @default.
- W4212913636 hasConcept C86803240 @default.
- W4212913636 hasConceptScore W4212913636C104317684 @default.
- W4212913636 hasConceptScore W4212913636C106358424 @default.
- W4212913636 hasConceptScore W4212913636C135763542 @default.
- W4212913636 hasConceptScore W4212913636C156719811 @default.
- W4212913636 hasConceptScore W4212913636C159047783 @default.
- W4212913636 hasConceptScore W4212913636C203014093 @default.
- W4212913636 hasConceptScore W4212913636C2522874641 @default.
- W4212913636 hasConceptScore W4212913636C2776029263 @default.
- W4212913636 hasConceptScore W4212913636C2776408679 @default.
- W4212913636 hasConceptScore W4212913636C2776455275 @default.
- W4212913636 hasConceptScore W4212913636C2780727368 @default.
- W4212913636 hasConceptScore W4212913636C2781463415 @default.
- W4212913636 hasConceptScore W4212913636C49105822 @default.
- W4212913636 hasConceptScore W4212913636C54355233 @default.
- W4212913636 hasConceptScore W4212913636C71924100 @default.
- W4212913636 hasConceptScore W4212913636C86803240 @default.
- W4212913636 hasIssue "1" @default.
- W4212913636 hasLocation W42129136361 @default.
- W4212913636 hasOpenAccess W4212913636 @default.
- W4212913636 hasPrimaryLocation W42129136361 @default.
- W4212913636 hasRelatedWork W2011626530 @default.
- W4212913636 hasRelatedWork W2021158901 @default.
- W4212913636 hasRelatedWork W2027655764 @default.
- W4212913636 hasRelatedWork W2038697911 @default.
- W4212913636 hasRelatedWork W2067312304 @default.
- W4212913636 hasRelatedWork W2068259734 @default.
- W4212913636 hasRelatedWork W2072233926 @default.
- W4212913636 hasRelatedWork W2118831589 @default.
- W4212913636 hasRelatedWork W3177527024 @default.
- W4212913636 hasRelatedWork W4212913636 @default.
- W4212913636 hasVolume "58" @default.
- W4212913636 isParatext "false" @default.
- W4212913636 isRetracted "false" @default.
- W4212913636 workType "article" @default.