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- W4212943630 endingPage "2236" @default.
- W4212943630 startingPage "2224" @default.
- W4212943630 abstract "Among antiviral drugs, the vast majority targets only one or two related viruses. The conventional model, one virus - one drug, significantly limits therapeutic options. Therefore, in the strategy of controlling viral infections, there is a necessity to develop compounds with pleiotropic effects. Favipiravir (FPV) emerged as a strong candidate to become such a drug. The aim of the study is to present up-to-date information on the role of favipiravir in the treatment of viral respiratory infections. The anti-influenza activity of favipiravir has been confirmed in cell culture experiments, animal models, and clinical trials. Thoroughly different - from the previously registered drugs - mechanism of action suggests that FVP can be used as a countermeasure for the novel or re-emerging influenza virus infections. In recent months, favipiravir has been broadly investigated due to its potential efficacy in the treatment of COVID-19. Based on preclinical and clinical studies and a recently published meta-analysis it seems that favipiravir may be a promising antiviral drug in the treatment of patients with COVID-19. FPV is also effective against other RNA respiratory viruses and may be a candidate for the treatment of serious infections caused by human rhinovirus, respiratory syncytial virus, metapneumovirus, parainfluenza viruses and hantavirus pulmonary syndrome." @default.
- W4212943630 created "2022-02-24" @default.
- W4212943630 creator A5069189857 @default.
- W4212943630 creator A5075899571 @default.
- W4212943630 date "2022-09-01" @default.
- W4212943630 modified "2023-09-26" @default.
- W4212943630 title "Favipiravir in the Battle with Respiratory Viruses" @default.
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- W4212943630 doi "https://doi.org/10.2174/1389557522666220218122744" @default.
- W4212943630 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35184710" @default.
- W4212943630 hasPublicationYear "2022" @default.
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