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• W4212980959 abstract "<sec> <title>BACKGROUND</title> Dietary quality plays an essential role in the prevention and management of metabolic syndrome (MetS). </sec> <sec> <title>OBJECTIVE</title> The aim of this pilot study is to organize personalized dietary advice in a real-life setting and to explore the effects on dietary intake, metabolic health, and perceived health. </sec> <sec> <title>METHODS</title> We followed a one-group pretest-posttest design and included 37 individuals at risk of MetS, who indicated motivation to change dietary behavior. For a period of 16 weeks, participants received personalized advice (t=0 and t=8) and feedback (t=0, t=4, t=8, t=12 and t=16) on dietary quality and metabolic health (ie, waist circumference, BMI, blood pressure, lipid profile, fasting glucose levels, and C-peptide). Personalized advice was generated in a two-stage process. In stage 1, an automated algorithm generated advice per food group, integrating data on individual dietary quality (Dutch Healthy Diet Index; total score 8-80) and metabolic health parameters. Stage 2 included a telephone consultation with a trained dietitian to define a personal dietary behavior change strategy and to discuss individual preferences. Dietary quality and metabolic health markers were assessed at t=0, t=8, and t=16. Self-perceived health was evaluated on 7-point Likert scales at t=0 and t=16. </sec> <sec> <title>RESULTS</title> At the end of the study period, dietary quality was significantly improved compared with the baseline (Dutch Healthy Diet Index +4.3; <i>P</i>&lt;.001). In addition, lipid profile (triglycerides, <i>P=.</i>02; total cholesterol, <i>P</i>=.01; high-density lipoprotein, <i>P</i>&lt;.001; and low-density lipoprotein, <i>P</i>&lt;.001), BMI (<i>P</i>&lt;.001), waist circumference (<i>P</i>=.01), and C-peptide (<i>P</i>=.01) were all significantly improved, whereas plasma glucose increased by 0.23 nmol/L (<i>P</i>=.04). In line with these results, self-perceived health scores were higher at t=16 weeks than at baseline (+0.67; <i>P</i>=.005). </sec> <sec> <title>CONCLUSIONS</title> This exploratory study showed that personalized dietary advice resulted in positive effects on dietary behavior, metabolic health, and self-perceived health in motivated pre-MetS adults. The study was performed in a do-it-yourself setting, highlighting the potential of at-home health improvement through dietary changes. </sec> <sec> <title>CLINICALTRIAL</title> ClinicalTrials.gov NCT04595669; https://clinicaltrials.gov/ct2/show/NCT04595669 </sec>" @default.
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• W4212980959 date "2020-10-15" @default.
• W4212980959 modified "2023-10-13" @default.
• W4212980959 title "Exploring the Potential of Personalized Dietary Advice for Health Improvement in Motivated Individuals With Premetabolic Syndrome: Pretest-Posttest Study (Preprint)" @default.
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• W4212980959 doi "https://doi.org/10.2196/preprints.25043" @default.
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