FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4213030695> ?p ?o ?g. }

• W4213030695 endingPage "19" @default.
• W4213030695 startingPage "15" @default.
• W4213030695 abstract "Background: Despite advancements in modern surgery and postoperative care, disruption of gastrointestinal anastomosis remains the most dreaded complication, even in experienced surgical hands. The cause of leakage is multifactorial consisting of a complete spectrum of pre, intra and postoperative factors. Search for an ideal gastrointestinal anastomosis still remains an unquenched thirst. Study Design: Prospective, hospital based, time bound observational study. Methods: After ethical clearance, 288 consenting adult patients who underwent gastrointestinal anastomosis were observed for risk factors, presentation and outcome of leakage and evaluated using appropriate statistical tools. Results: An overall gastrointestinal anastomotic leak rate of 15.28% with peak incidence at 41-50 years (19.51%) was seen. Peritonitis (p=0.0009, OR=2.9611), COPD (p=0.0181, OR=2.7306), low serum albumin concentration (p=0.0028, OR=3.1442), ASA status of ≥III (p=0.0001, OR=4.0281) and a perioperative blood transfusion requirement of ≥2 units (p=0.0028, OR=3.1442) were the most signicant risk factors associated with leakage. Obstruction (p=0.0160, OR=2.2310), malignancy (p=0.0149, OR=2.6961), steroid therapy (p=0.0176, OR=2.2741), chemoradiation (p=0.0400, OR=2.4889), diabetes (p=0.0427, OR=2.2689), undernutrition (p= 0.0308, OR= 2.1099), anaemia (p=0.0325, OR=2.0183) and sepsis (p=0.0187, OR=2.2702) also showed clear risk augmentation. Risk of leakage was increased with a surgical duration of >4 hours (p=0.0078, OR=2.5610), when anastomosis was done as an emergency procedure (p=0.0427, OR=2.6571) or by a surgeon with expertise of ≤5 years (p=0.0338, OR=2.7733). Neither the level, type, technique of anastomosis; nor the usage of surgical staplers had an impact on leakage. Preoperative bowel preparation and creation of a proximal stoma also had minimal effect on leakage rates; though, the infectious complications that follow were greatly reduced. The most common presentation of anastomotic leak was a suspicious drain output with a mean time of 7.59± 2(2.48) postoperative days; resulting in a prolongation of hospitalization by more than ten days (p<0.0001), along with an increased mortality rate (p<0.0001). Conclusions: Accurately predicting anastomotic leakage still requires more evidence-based information. Even with good risk stratication, many causative factors may not be amenable to immediate correction in the pre-operative period. In such cases, the patient must be considered as a candidate for an enterostomy to help tide the crisis over." @default.
• W4213030695 created "2022-02-24" @default.
• W4213030695 creator A5001297619 @default.
• W4213030695 creator A5044033229 @default.
• W4213030695 creator A5088514283 @default.
• W4213030695 creator A5090427405 @default.
• W4213030695 date "2021-07-01" @default.
• W4213030695 modified "2023-10-18" @default.
• W4213030695 title "A PROSPECTIVE ANALYSIS OF RISK FACTORS, PRESENTATION AND OUTCOME OF LEAKAGE AFTER GASTROINTESTINAL ANASTOMOSES" @default.
• W4213030695 cites W1598547511 @default.
• W4213030695 cites W18847279 @default.
• W4213030695 cites W1969969599 @default.
• W4213030695 cites W1971156532 @default.
• W4213030695 cites W1976212944 @default.
• W4213030695 cites W1992736504 @default.
• W4213030695 cites W2005716046 @default.
• W4213030695 cites W2016288162 @default.
• W4213030695 cites W2040198839 @default.
• W4213030695 cites W2066256605 @default.
• W4213030695 cites W2071450936 @default.
• W4213030695 cites W2098111834 @default.
• W4213030695 cites W2112388242 @default.
• W4213030695 cites W2123834062 @default.
• W4213030695 cites W2244101739 @default.
• W4213030695 cites W2569015222 @default.
• W4213030695 cites W2991188113 @default.
• W4213030695 cites W4240459497 @default.
• W4213030695 doi "https://doi.org/10.36106/ijar/5402879" @default.
• W4213030695 hasPublicationYear "2021" @default.
• W4213030695 type Work @default.
• W4213030695 citedByCount "0" @default.
• W4213030695 crossrefType "journal-article" @default.
• W4213030695 hasAuthorship W4213030695A5001297619 @default.
• W4213030695 hasAuthorship W4213030695A5044033229 @default.
• W4213030695 hasAuthorship W4213030695A5088514283 @default.
• W4213030695 hasAuthorship W4213030695A5090427405 @default.
• W4213030695 hasConcept C126322002 @default.
• W4213030695 hasConcept C134018914 @default.
• W4213030695 hasConcept C141071460 @default.
• W4213030695 hasConcept C188816634 @default.
• W4213030695 hasConcept C2778384902 @default.
• W4213030695 hasConcept C2780199535 @default.
• W4213030695 hasConcept C31174226 @default.
• W4213030695 hasConcept C555293320 @default.
• W4213030695 hasConcept C71924100 @default.
• W4213030695 hasConcept C8443397 @default.
• W4213030695 hasConcept C90924648 @default.
• W4213030695 hasConceptScore W4213030695C126322002 @default.
• W4213030695 hasConceptScore W4213030695C134018914 @default.
• W4213030695 hasConceptScore W4213030695C141071460 @default.
• W4213030695 hasConceptScore W4213030695C188816634 @default.
• W4213030695 hasConceptScore W4213030695C2778384902 @default.
• W4213030695 hasConceptScore W4213030695C2780199535 @default.
• W4213030695 hasConceptScore W4213030695C31174226 @default.
• W4213030695 hasConceptScore W4213030695C555293320 @default.
• W4213030695 hasConceptScore W4213030695C71924100 @default.
• W4213030695 hasConceptScore W4213030695C8443397 @default.
• W4213030695 hasConceptScore W4213030695C90924648 @default.
• W4213030695 hasLocation W42130306951 @default.
• W4213030695 hasOpenAccess W4213030695 @default.
• W4213030695 hasPrimaryLocation W42130306951 @default.
• W4213030695 hasRelatedWork W11570135 @default.
• W4213030695 hasRelatedWork W12460284 @default.
• W4213030695 hasRelatedWork W13650667 @default.
• W4213030695 hasRelatedWork W14698401 @default.
• W4213030695 hasRelatedWork W20529376 @default.
• W4213030695 hasRelatedWork W20874726 @default.
• W4213030695 hasRelatedWork W227432 @default.
• W4213030695 hasRelatedWork W2911026 @default.
• W4213030695 hasRelatedWork W6122712 @default.
• W4213030695 hasRelatedWork W9133611 @default.
• W4213030695 isParatext "false" @default.
• W4213030695 isRetracted "false" @default.
• W4213030695 workType "article" @default.