FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4213043984> ?p ?o ?g. }

• W4213043984 endingPage "e0263927" @default.
• W4213043984 startingPage "e0263927" @default.
• W4213043984 abstract "Background Clinical practice guidelines recommend administering antenatal corticosteroids (ACS), either betamethasone or dexamethasone, to women at risk of preterm birth at less than 35 weeks’ gestation. If women remain at risk of preterm birth seven or more days after an initial course of ACS, most guidelines recommend administration of a repeat dose(s). No randomised trials have assessed the efficacy of dexamethasone as a repeat steroid compared to betamethasone. Aim We aimed to determine if there were differences between the use of dexamethasone or betamethasone as repeat ACS, for women who remain at risk of preterm birth after an initial course, on maternal, infant, and childhood health outcomes. Methods We performed a secondary analysis of data from the ASTEROID randomised trial, where women at risk of preterm birth were allocated to either betamethasone or dexamethasone. Infant, childhood, and maternal outcomes were compared according to whether women received a repeat dose(s) of dexamethasone or betamethasone. The primary outcome was a composite outcome of death or any neurosensory disability at age two years (corrected for prematurity). The ASTEROID trial is registered with ANZCTR, ACTRN12608000631303. Results 168 women and their infants were included, with 86 women receiving dexamethasone and 82 women receiving betamethasone as a repeat dose. Women in the two ACS groups had similar baseline characteristics. We observed little to no difference in the incidence of death or any neurosensory disability at age two years (OR 0.89, 95% CI 0.39 to 2.06, p = 0.79) or in the incidence of other infant, childhood, and maternal adverse health outcomes between women who received dexamethasone and those who received betamethasone. Conclusion Use of dexamethasone for a repeat dose(s) compared to betamethasone did not result in any differences in infant, childhood, and maternal health outcomes. These results can be used to support clinical practice guideline recommendations." @default.
• W4213043984 created "2022-02-24" @default.
• W4213043984 creator A5003620404 @default.
• W4213043984 creator A5020727065 @default.
• W4213043984 creator A5023252382 @default.
• W4213043984 creator A5084711970 @default.
• W4213043984 date "2022-02-22" @default.
• W4213043984 modified "2023-09-30" @default.
• W4213043984 title "Maternal and infant morbidity following administration of repeat dexamethasone or betamethasone prior to preterm birth: A secondary analysis of the ASTEROID Trial" @default.
• W4213043984 cites W1951503122 @default.
• W4213043984 cites W2017975444 @default.
• W4213043984 cites W2105621974 @default.
• W4213043984 cites W2169101968 @default.
• W4213043984 cites W2313210773 @default.
• W4213043984 cites W2935719175 @default.
• W4213043984 cites W2972733683 @default.
• W4213043984 cites W4234794804 @default.
• W4213043984 doi "https://doi.org/10.1371/journal.pone.0263927" @default.
• W4213043984 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35192656" @default.
• W4213043984 hasPublicationYear "2022" @default.
• W4213043984 type Work @default.
• W4213043984 citedByCount "1" @default.
• W4213043984 countsByYear W42130439842022 @default.
• W4213043984 crossrefType "journal-article" @default.
• W4213043984 hasAuthorship W4213043984A5003620404 @default.
• W4213043984 hasAuthorship W4213043984A5020727065 @default.
• W4213043984 hasAuthorship W4213043984A5023252382 @default.
• W4213043984 hasAuthorship W4213043984A5084711970 @default.
• W4213043984 hasBestOaLocation W42130439841 @default.
• W4213043984 hasConcept C120665830 @default.
• W4213043984 hasConcept C121332964 @default.
• W4213043984 hasConcept C126322002 @default.
• W4213043984 hasConcept C131872663 @default.
• W4213043984 hasConcept C141071460 @default.
• W4213043984 hasConcept C168563851 @default.
• W4213043984 hasConcept C187212893 @default.
• W4213043984 hasConcept C2776344615 @default.
• W4213043984 hasConcept C2779234561 @default.
• W4213043984 hasConcept C2780401358 @default.
• W4213043984 hasConcept C2781162121 @default.
• W4213043984 hasConcept C46973012 @default.
• W4213043984 hasConcept C54355233 @default.
• W4213043984 hasConcept C61511704 @default.
• W4213043984 hasConcept C71924100 @default.
• W4213043984 hasConcept C86803240 @default.
• W4213043984 hasConceptScore W4213043984C120665830 @default.
• W4213043984 hasConceptScore W4213043984C121332964 @default.
• W4213043984 hasConceptScore W4213043984C126322002 @default.
• W4213043984 hasConceptScore W4213043984C131872663 @default.
• W4213043984 hasConceptScore W4213043984C141071460 @default.
• W4213043984 hasConceptScore W4213043984C168563851 @default.
• W4213043984 hasConceptScore W4213043984C187212893 @default.
• W4213043984 hasConceptScore W4213043984C2776344615 @default.
• W4213043984 hasConceptScore W4213043984C2779234561 @default.
• W4213043984 hasConceptScore W4213043984C2780401358 @default.
• W4213043984 hasConceptScore W4213043984C2781162121 @default.
• W4213043984 hasConceptScore W4213043984C46973012 @default.
• W4213043984 hasConceptScore W4213043984C54355233 @default.
• W4213043984 hasConceptScore W4213043984C61511704 @default.
• W4213043984 hasConceptScore W4213043984C71924100 @default.
• W4213043984 hasConceptScore W4213043984C86803240 @default.
• W4213043984 hasFunder F4320334705 @default.
• W4213043984 hasIssue "2" @default.
• W4213043984 hasLocation W42130439841 @default.
• W4213043984 hasLocation W42130439842 @default.
• W4213043984 hasLocation W42130439843 @default.
• W4213043984 hasLocation W42130439844 @default.
• W4213043984 hasLocation W42130439845 @default.
• W4213043984 hasLocation W42130439846 @default.
• W4213043984 hasOpenAccess W4213043984 @default.
• W4213043984 hasPrimaryLocation W42130439841 @default.
• W4213043984 hasRelatedWork W1968618711 @default.
• W4213043984 hasRelatedWork W2057772858 @default.
• W4213043984 hasRelatedWork W2330569613 @default.
• W4213043984 hasRelatedWork W3048306897 @default.
• W4213043984 hasRelatedWork W3163987424 @default.
• W4213043984 hasRelatedWork W3181785047 @default.
• W4213043984 hasRelatedWork W4232087044 @default.
• W4213043984 hasRelatedWork W4245066087 @default.
• W4213043984 hasRelatedWork W4281694272 @default.
• W4213043984 hasRelatedWork W985205842 @default.
• W4213043984 hasVolume "17" @default.
• W4213043984 isParatext "false" @default.
• W4213043984 isRetracted "false" @default.
• W4213043984 workType "article" @default.