Matches in SemOpenAlex for { <https://semopenalex.org/work/W4213060319> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W4213060319 endingPage "31" @default.
- W4213060319 startingPage "25" @default.
- W4213060319 abstract "Effectiveness of hydroxychloroquine against SARS-CoV-2 has been highly controversial. In our research, we aimed to investigate the effects of hydroxychloroquine on disease outcomes in hospitalized patients with COVID-19.A total of 393 hospitalized patients with COVID-19 were retrospectively assigned to the standard of care therapy group (n = 180) or the standard of care plus hydroxychloroquine group (n = 213). The standard of care therapy comprised favipiravir, low molecular weight heparin, acetylsalicylic acid. Status of oxygenation at baseline and on the seventh day, laboratory tests at baseline and at discharge were recorded. Length of hospital stay, administration of anti-inflammatory treatment, admission to the intensive care unit and 28th day mortality were set as primary endpoints.There were no statistically significant differences between groups in terms of oxygen delivery route and mortality after seven days of treatment (p = 0.592). C-reactive protein levels of the standard of care plus hydroxychloroquine group were significantly lower than that of the standard of care group at discharge (p = 0.034). Patients in the standard of care plus hydroxychloroquine group had shorter hospital stay (p = 0.007). The standard of care plus hydroxychloroquine group was favored over standard of care group in terms of rate of intensive care unit admissions (21.7% vs. 10.8%; relative risk with 95% CI = 0.49 [0.31-0.80], p = 0.003).Hydroxychloroquine in addition to standard of care was associated with less intensive care unit admissions, early discharge and greater C-reactive protein reduction. There was no difference in 28-day mortality." @default.
- W4213060319 created "2022-02-24" @default.
- W4213060319 creator A5005261320 @default.
- W4213060319 creator A5014114164 @default.
- W4213060319 creator A5014117586 @default.
- W4213060319 creator A5024427640 @default.
- W4213060319 creator A5029672459 @default.
- W4213060319 creator A5037870873 @default.
- W4213060319 creator A5045794003 @default.
- W4213060319 creator A5059943791 @default.
- W4213060319 creator A5064709497 @default.
- W4213060319 creator A5072082690 @default.
- W4213060319 creator A5087693961 @default.
- W4213060319 date "2022-01-31" @default.
- W4213060319 modified "2023-10-18" @default.
- W4213060319 title "Hydroxychloroquine shortened hospital stay and reduced intensive care unit admissions in hospitalized COVID-19 patients" @default.
- W4213060319 doi "https://doi.org/10.3855/jidc.14933" @default.
- W4213060319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35192518" @default.
- W4213060319 hasPublicationYear "2022" @default.
- W4213060319 type Work @default.
- W4213060319 citedByCount "0" @default.
- W4213060319 crossrefType "journal-article" @default.
- W4213060319 hasAuthorship W4213060319A5005261320 @default.
- W4213060319 hasAuthorship W4213060319A5014114164 @default.
- W4213060319 hasAuthorship W4213060319A5014117586 @default.
- W4213060319 hasAuthorship W4213060319A5024427640 @default.
- W4213060319 hasAuthorship W4213060319A5029672459 @default.
- W4213060319 hasAuthorship W4213060319A5037870873 @default.
- W4213060319 hasAuthorship W4213060319A5045794003 @default.
- W4213060319 hasAuthorship W4213060319A5059943791 @default.
- W4213060319 hasAuthorship W4213060319A5064709497 @default.
- W4213060319 hasAuthorship W4213060319A5072082690 @default.
- W4213060319 hasAuthorship W4213060319A5087693961 @default.
- W4213060319 hasBestOaLocation W42130603191 @default.
- W4213060319 hasConcept C126322002 @default.
- W4213060319 hasConcept C177713679 @default.
- W4213060319 hasConcept C187212893 @default.
- W4213060319 hasConcept C194828623 @default.
- W4213060319 hasConcept C2776376669 @default.
- W4213060319 hasConcept C2779123688 @default.
- W4213060319 hasConcept C2779134260 @default.
- W4213060319 hasConcept C2987404301 @default.
- W4213060319 hasConcept C2993769353 @default.
- W4213060319 hasConcept C3008058167 @default.
- W4213060319 hasConcept C524204448 @default.
- W4213060319 hasConcept C71924100 @default.
- W4213060319 hasConceptScore W4213060319C126322002 @default.
- W4213060319 hasConceptScore W4213060319C177713679 @default.
- W4213060319 hasConceptScore W4213060319C187212893 @default.
- W4213060319 hasConceptScore W4213060319C194828623 @default.
- W4213060319 hasConceptScore W4213060319C2776376669 @default.
- W4213060319 hasConceptScore W4213060319C2779123688 @default.
- W4213060319 hasConceptScore W4213060319C2779134260 @default.
- W4213060319 hasConceptScore W4213060319C2987404301 @default.
- W4213060319 hasConceptScore W4213060319C2993769353 @default.
- W4213060319 hasConceptScore W4213060319C3008058167 @default.
- W4213060319 hasConceptScore W4213060319C524204448 @default.
- W4213060319 hasConceptScore W4213060319C71924100 @default.
- W4213060319 hasIssue "01" @default.
- W4213060319 hasLocation W42130603191 @default.
- W4213060319 hasLocation W42130603192 @default.
- W4213060319 hasOpenAccess W4213060319 @default.
- W4213060319 hasPrimaryLocation W42130603191 @default.
- W4213060319 hasRelatedWork W1984498786 @default.
- W4213060319 hasRelatedWork W2000329364 @default.
- W4213060319 hasRelatedWork W2057630253 @default.
- W4213060319 hasRelatedWork W2274076556 @default.
- W4213060319 hasRelatedWork W2327606279 @default.
- W4213060319 hasRelatedWork W2331454882 @default.
- W4213060319 hasRelatedWork W2362037864 @default.
- W4213060319 hasRelatedWork W2474790959 @default.
- W4213060319 hasRelatedWork W2753993308 @default.
- W4213060319 hasRelatedWork W3047805513 @default.
- W4213060319 hasVolume "16" @default.
- W4213060319 isParatext "false" @default.
- W4213060319 isRetracted "false" @default.
- W4213060319 workType "article" @default.