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- W4213062641 abstract "<dm:abstracts xmlns:dm=http://www.elsevier.com/xml/dm/dtd><ce:abstract xmlns:ce=http://www.elsevier.com/xml/common/dtd view=all class=author id=aep-abstract-id8><ce:section-title>Publisher Summary</ce:section-title><ce:abstract-sec view=all id=aep-abstract-sec-id9><ce:simple-para id=fsabs017 view=all>This chapter includes definition and principles of nephelometry and turbidimetry. Light is scattered in all directions when it passes through a transparent medium containing particles from a secondary phase manifestation of an antibody–antigen immunoprecipitation reaction. Nephelometry and turbidimetry are general terms used to refer to the measurement of scattered light. For many antigen–antibody systems, the measurement of the primary binding of an antibody to its specific antigen, which occurs rapidly in a solution, is observed and measured by an increase in light scatter at various angles to the incident light. The presence of small immune complexes formed in antibody excess causes the light scatter to occur, and as long as the complexes remain small in relation to the wavelength of the incident light, the intensity of the light scattered is proportional to the molecular weight and concentration of the complexes formed. These types of measurements are valid when the reactants are in a dilute solution. With the current availability of nephelometric and turbidimetric instruments, the specific measurement of serum proteins and other serum analytes can be generated rapidly and with significant cost effectiveness.</ce:simple-para></ce:abstract-sec></ce:abstract></dm:abstracts>" @default.
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- W4213062641 date "1921-08-01" @default.
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- W4213062641 title "Substitution of turbidity for nephelometry" @default.
- W4213062641 doi "https://doi.org/10.1016/s0016-0032(21)90918-9" @default.
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