Matches in SemOpenAlex for { <https://semopenalex.org/work/W4213111898> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W4213111898 endingPage "242" @default.
- W4213111898 startingPage "241" @default.
- W4213111898 abstract "We read with interest the correspondence of Dr. Güler concerning our article.1 In this article we described the common therapies used for the treatment of true extramedullary plasmacytomas (EMPs). These tumors are sensitive to radiotherapy and more often appear in the upper aerodigestive tract. The response rate after radiotherapy is very high, as indicated in the literature.2, 3 Furthermore, our retrospective investigations have revealed that the combination of radiotherapy and surgery provides the best survival rate, especially for patients with an EMP in the upper aerodigestive area.1 EMPs that occur in regions outside of the upper aerodigestive tract are treated mainly by surgery. Chemotherapy has been given only in rare cases, and the use of adjuvant chemotherapy has not affected the rate of conversion to myeloma.2 Soesan et al., who were mentioned in the correspondence, achieved local control in 9 out of 18 patients treated with primary surgery and in 8 out of 12 patients treated with initial radiotherapy. In 11 out of 19 patients they received local control with chemotherapy. They observed 35 patients in their study group.4 Because true EMP affects localized regions, surgical excision is very effective and does not show the major negative side effects seen with chemotherapy. If complete removal of an EMP is not possible, radiotherapy should also be administered. Chemotherapy is the domain of disseminated diseases, i.e., multiple myeloma. However, in rare instances, if the EMP is very large and adjacent vital organ structures preclude radical intervention, preoperative chemotherapy may be helpful in reducing the size of the plasmacytoma to enable organ preservation. Postoperative radiotherapy should be applied in all of these cases. Christoph Alexiou M.D.*, Wolfgang Arnold M.D. , * Department of Otorhinolaryngology, Head and, Neck Surgery, Technical University of Munich, Munich, Germany, Head of the Department of Otorhinolaryngology, Head and Neck Surgery, Technical University of Munich, Munich, Germany" @default.
- W4213111898 created "2022-02-24" @default.
- W4213111898 creator A5012400250 @default.
- W4213111898 creator A5069653971 @default.
- W4213111898 date "2000-01-01" @default.
- W4213111898 modified "2023-09-27" @default.
- W4213111898 title "Author reply" @default.
- W4213111898 doi "https://doi.org/10.1002/(sici)1097-0142(20000101)88:1<241::aid-cncr34>3.3.co;2-h" @default.
- W4213111898 hasPublicationYear "2000" @default.
- W4213111898 type Work @default.
- W4213111898 citedByCount "0" @default.
- W4213111898 crossrefType "journal-article" @default.
- W4213111898 hasAuthorship W4213111898A5012400250 @default.
- W4213111898 hasAuthorship W4213111898A5069653971 @default.
- W4213111898 hasBestOaLocation W42131118981 @default.
- W4213111898 hasConcept C121608353 @default.
- W4213111898 hasConcept C126322002 @default.
- W4213111898 hasConcept C141071460 @default.
- W4213111898 hasConcept C2776364478 @default.
- W4213111898 hasConcept C2776694085 @default.
- W4213111898 hasConcept C2776874909 @default.
- W4213111898 hasConcept C3018227240 @default.
- W4213111898 hasConcept C509974204 @default.
- W4213111898 hasConcept C530470458 @default.
- W4213111898 hasConcept C71924100 @default.
- W4213111898 hasConceptScore W4213111898C121608353 @default.
- W4213111898 hasConceptScore W4213111898C126322002 @default.
- W4213111898 hasConceptScore W4213111898C141071460 @default.
- W4213111898 hasConceptScore W4213111898C2776364478 @default.
- W4213111898 hasConceptScore W4213111898C2776694085 @default.
- W4213111898 hasConceptScore W4213111898C2776874909 @default.
- W4213111898 hasConceptScore W4213111898C3018227240 @default.
- W4213111898 hasConceptScore W4213111898C509974204 @default.
- W4213111898 hasConceptScore W4213111898C530470458 @default.
- W4213111898 hasConceptScore W4213111898C71924100 @default.
- W4213111898 hasIssue "1" @default.
- W4213111898 hasLocation W42131118981 @default.
- W4213111898 hasOpenAccess W4213111898 @default.
- W4213111898 hasPrimaryLocation W42131118981 @default.
- W4213111898 hasRelatedWork W1535958986 @default.
- W4213111898 hasRelatedWork W167319750 @default.
- W4213111898 hasRelatedWork W190310987 @default.
- W4213111898 hasRelatedWork W200989379 @default.
- W4213111898 hasRelatedWork W2322768082 @default.
- W4213111898 hasRelatedWork W2393257836 @default.
- W4213111898 hasRelatedWork W2409628717 @default.
- W4213111898 hasRelatedWork W2474806879 @default.
- W4213111898 hasRelatedWork W271211968 @default.
- W4213111898 hasRelatedWork W4252738781 @default.
- W4213111898 hasVolume "88" @default.
- W4213111898 isParatext "false" @default.
- W4213111898 isRetracted "false" @default.
- W4213111898 workType "article" @default.