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- W4213133091 abstract "IL-31 represents a novel cytokine involved in pruritic skin diseases including atopic dermatitis (AD). We, therefore, aimed at investigating IL-31 levels in chronic spontaneous urticaria (CU). We included 46 patients with CU, 26 non-atopic skin healthy subjects as negative and 28 patients with AD as positive controls. IL-31 serum levels were analysed using commercial ELISA kit. IL-31 serum levels were higher in patients with CU compared to healthy controls (P < 0.001), but lower compared to patients with AD (P < 0.001). There was no difference in IL-31 serum levels in autologous serum skin test positive or negative CU patients and patients with infectious trigger factors including helicobacter pylori infection. IL-31 serum levels may play a role in the pathophysiology of CU. This is supported by the finding that not all patients with CU respond to antihistamine treatment but to the treatment with immunosuppressive drugs. PMID: 20163453" @default.
- W4213133091 created "2022-02-24" @default.
- W4213133091 creator A5015789010 @default.
- W4213133091 date "2010-03-26" @default.
- W4213133091 modified "2023-09-23" @default.
- W4213133091 title "Faculty Opinions recommendation of Increased levels of serum IL-31 in chronic spontaneous urticaria." @default.
- W4213133091 doi "https://doi.org/10.3410/f.2693958.2356058" @default.
- W4213133091 hasPublicationYear "2010" @default.
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