FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4213203483> ?p ?o ?g. }

• W4213203483 endingPage "e2148329" @default.
• W4213203483 startingPage "e2148329" @default.
• W4213203483 abstract "No data exist on time to recovery of patient-reported and performance-related measures of functional independence after radical cystectomy (open or robotic).To determine recovery of functional independence after radical cystectomy and whether robot-assisted radical cystectomy (RARC) is associated with any advantage over open procedures.Data for this secondary analysis from the RAZOR (Randomized Open vs Robotic Cystectomy) trial were used. RAZOR was a phase 3 multicenter noninferiority trial across 15 academic medical centers in the US from July 1, 2011, to November 18, 2014, with a median follow-up of 2 years. Participants included the per-protocol population (n = 302). Data were analyzed from February 1, 2017, to May 1, 2021.Robot-assisted radical cystectomy or open radical cystectomy (ORC).Patient-reported (activities of daily living [ADL] and independent ADL [iADL]) and performance-related (hand grip strength [HGS] and Timed Up & Go walking test [TUGWT]) measures of independence were assessed. Patterns of postoperative recovery for the entire cohort and comparisons between RARC and ORC were performed. Exploratory analyses to assess measures of independence across diversion type and to determine whether baseline impairments were associated with 90-day complications or 1-year mortality were performed.Of the 302 patients included in the analysis (254 men [84.1%]; mean [SD] age at consent, 68.0 [9.7] years), 150 underwent RARC and 152 underwent ORC. Baseline characteristics were similar in both groups. For the entire cohort, ADL, iADL, and TUGWT recovered to baseline by 3 postoperative months, whereas HGS recovered by 6 months. There was no difference between RARC and ORC for ADL, iADL, TUGWT, or HGS scores at any time. Activities of daily living recovered 1 month after RARC (mean estimated score, 7.7 [95% CI, 7.3-8.0]) vs 3 months after ORC (mean estimated score, 7.5 [95% CI, 7.2-7.8]). Hand grip strength recovered by 3 months after RARC (mean estimated HGS, 29.0 [95% CI, 26.3-31.7] kg) vs 6 months after ORC (mean estimated HGS, 31.2 [95% CI, 28.8-34.2] kg). In the RARC group, 32 of 90 patients (35.6%) showed a recovery in HGS at 3 months vs 32 of 88 (36.4%) in the ORC group (P = .91), indicating a rejection of the primary study hypothesis for HGS. Independent ADL and TUGWT recovered in 3 months for both approaches. Hand grip strength showed earlier recovery in patients undergoing continent urinary diversion (mean HGS at 3 months, 31.3 [95% CI, 27.7-34.8] vs 33.9 [95% CI, 30.5-37.3] at baseline; P = .09) than noncontinent urinary diversion (mean HGS at 6 months, 27.4 [95% CI, 24.9-30.0] vs 29.5 [95% CI, 27.2-31.9] kg at baseline; P = .02), with no differences in other parameters. Baseline impairments in any parameter were not associated with 90-day complications or 1-year mortality.The results of this secondary analysis suggest that patients require 3 to 6 months to recover baseline levels after radical cystectomy irrespective of surgical approach. These data will be invaluable in patient counseling and preparation. Hand grip strength and ADL tended to recover to baseline earlier after RARC; however, there was no difference in the percentage of patients recovering when compared with ORC. Further study is needed to assess the clinical significance of these findings.ClinicalTrials.gov Identifier: NCT01157676." @default.
• W4213203483 created "2022-02-24" @default.
• W4213203483 creator A5000564724 @default.
• W4213203483 creator A5004285397 @default.
• W4213203483 creator A5008039593 @default.
• W4213203483 creator A5008808406 @default.
• W4213203483 creator A5016811631 @default.
• W4213203483 creator A5018208869 @default.
• W4213203483 creator A5030755763 @default.
• W4213203483 creator A5046653328 @default.
• W4213203483 creator A5052021735 @default.
• W4213203483 creator A5058251204 @default.
• W4213203483 creator A5058744124 @default.
• W4213203483 creator A5062422300 @default.
• W4213203483 creator A5064387672 @default.
• W4213203483 creator A5066279767 @default.
• W4213203483 creator A5069174478 @default.
• W4213203483 creator A5083724892 @default.
• W4213203483 date "2022-02-16" @default.
• W4213203483 modified "2023-10-16" @default.
• W4213203483 title "Comparison of Robot-Assisted and Open Radical Cystectomy in Recovery of Patient-Reported and Performance-Related Measures of Independence" @default.
• W4213203483 cites W1994053739 @default.
• W4213203483 cites W2029131477 @default.
• W4213203483 cites W2036876891 @default.
• W4213203483 cites W2048237362 @default.
• W4213203483 cites W2064874457 @default.
• W4213203483 cites W2067131061 @default.
• W4213203483 cites W2068020336 @default.
• W4213203483 cites W2094767169 @default.
• W4213203483 cites W2096998881 @default.
• W4213203483 cites W2140092212 @default.
• W4213203483 cites W2149136913 @default.
• W4213203483 cites W2151980973 @default.
• W4213203483 cites W2165535994 @default.
• W4213203483 cites W2809685212 @default.
• W4213203483 cites W2886402253 @default.
• W4213203483 cites W2914799264 @default.
• W4213203483 cites W2941911694 @default.
• W4213203483 cites W2955125638 @default.
• W4213203483 cites W2975105339 @default.
• W4213203483 cites W3015949572 @default.
• W4213203483 cites W3045582789 @default.
• W4213203483 cites W3046256109 @default.
• W4213203483 cites W4249999102 @default.
• W4213203483 doi "https://doi.org/10.1001/jamanetworkopen.2021.48329" @default.
• W4213203483 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35171260" @default.
• W4213203483 hasPublicationYear "2022" @default.
• W4213203483 type Work @default.
• W4213203483 citedByCount "11" @default.
• W4213203483 countsByYear W42132034832022 @default.
• W4213203483 countsByYear W42132034832023 @default.
• W4213203483 crossrefType "journal-article" @default.
• W4213203483 hasAuthorship W4213203483A5000564724 @default.
• W4213203483 hasAuthorship W4213203483A5004285397 @default.
• W4213203483 hasAuthorship W4213203483A5008039593 @default.
• W4213203483 hasAuthorship W4213203483A5008808406 @default.
• W4213203483 hasAuthorship W4213203483A5016811631 @default.
• W4213203483 hasAuthorship W4213203483A5018208869 @default.
• W4213203483 hasAuthorship W4213203483A5030755763 @default.
• W4213203483 hasAuthorship W4213203483A5046653328 @default.
• W4213203483 hasAuthorship W4213203483A5052021735 @default.
• W4213203483 hasAuthorship W4213203483A5058251204 @default.
• W4213203483 hasAuthorship W4213203483A5058744124 @default.
• W4213203483 hasAuthorship W4213203483A5062422300 @default.
• W4213203483 hasAuthorship W4213203483A5064387672 @default.
• W4213203483 hasAuthorship W4213203483A5066279767 @default.
• W4213203483 hasAuthorship W4213203483A5069174478 @default.
• W4213203483 hasAuthorship W4213203483A5083724892 @default.
• W4213203483 hasBestOaLocation W42132034831 @default.
• W4213203483 hasConcept C121608353 @default.
• W4213203483 hasConcept C126322002 @default.
• W4213203483 hasConcept C141071460 @default.
• W4213203483 hasConcept C1862650 @default.
• W4213203483 hasConcept C2775910329 @default.
• W4213203483 hasConcept C2780352672 @default.
• W4213203483 hasConcept C2908647359 @default.
• W4213203483 hasConcept C71924100 @default.
• W4213203483 hasConcept C72563966 @default.
• W4213203483 hasConcept C79544238 @default.
• W4213203483 hasConcept C99454951 @default.
• W4213203483 hasConceptScore W4213203483C121608353 @default.
• W4213203483 hasConceptScore W4213203483C126322002 @default.
• W4213203483 hasConceptScore W4213203483C141071460 @default.
• W4213203483 hasConceptScore W4213203483C1862650 @default.
• W4213203483 hasConceptScore W4213203483C2775910329 @default.
• W4213203483 hasConceptScore W4213203483C2780352672 @default.
• W4213203483 hasConceptScore W4213203483C2908647359 @default.
• W4213203483 hasConceptScore W4213203483C71924100 @default.
• W4213203483 hasConceptScore W4213203483C72563966 @default.
• W4213203483 hasConceptScore W4213203483C79544238 @default.
• W4213203483 hasConceptScore W4213203483C99454951 @default.
• W4213203483 hasIssue "2" @default.
• W4213203483 hasLocation W42132034831 @default.
• W4213203483 hasLocation W42132034832 @default.
• W4213203483 hasLocation W42132034833 @default.
• W4213203483 hasOpenAccess W4213203483 @default.
• W4213203483 hasPrimaryLocation W42132034831 @default.
• W4213203483 hasRelatedWork W2003938723 @default.

• next