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- W4213211982 abstract "Regulation of the cell cycle involves the nedd8 ubiquitin-like modification of key proteins. Kurz et al. now find that these modifications are also important in controlling the cytoskeleton in Caenorhabditis elegans embryos. Nedd 8 conjugation inhibits microfilament contraction in the cell cortex during pronuclear migration and again during cytokinesis. In addition, katanin, a microtubule-severing complex, is degraded after neddylation at the end of meiosis.T. Kurz, L. Pintard, J. H. Wills, D. R. Hamill, P. Gönczy, M. Peter, B. Bowerman, Cytoskeletal regulation by the nedd8 ubiquitin-like protein modification pathway. Science 295, 1294-1298 (2002).[Abstract][Full Text]" @default.
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- W4213211982 date "2002-02-19" @default.
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- W4213211982 title "Doing Double Duty" @default.
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