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- W4213215300 abstract "Abstract Background The aim of this study is to examine the diagnostic value of MRI of the resected specimen ( smr ) of rectal cancer in terms of pathological circumferential resection margin (pCRM). Methods Twenty-three patients with middle to low rectal cancer underwent laparoscopic radical surgery from March 2017 to April 2018, and smr was performed. Two radiologists interpreted smr with the pathological findings blinded. We examined two categories in the accuracy comparison with pCRM; 1) correlation betweenzand pCRM and correlation between smr CRM and pCRM. 2) diagnostic accuracy of smr in identifying the mesorectal lymph-nodes (LN) and tumor deposit (TD) that should be taken into consideration in the CRM measurements. Results Patient characteristics (median): male 18, female 5, Age 67 years (45-79), Anal verge 8.0cm (0-13.0), pre-operative chemoradiotherapy + / -:10/13, Surgical procedure low anterior reaction (LAR)/ abdominoperineal resection (APR)/ total pelvic exenteration (TPE):20/2/1. pT x/1/2/3:1/1/3/18, pN 0/1a/1b/1c/2b:12/5/2/3/1. pStage X/I/IIA/ IIIA/IIIB/IIIC:1/3/8/1/9/1.1) Sixteen cases of TME surgery were examined correlation between in-vivoCRM, smr CRM and pCRM. Spearman’s rank correlation coefficient and a simple regression analysis revealed a significant correlation between in-vivoCRM (p <0·001, p<0.05), smr CRM(p <0·001, p<0.01) and pCRM. The correlation coefficient between smr CRM and pCRM was stronger than that between in-vivoCRM and pCRM. 2) Ninety-six mesorectal nodules included: pLN (-) 77, pLN (+) 10, TD 9, and kappa value of diagnostic agreement for each radiologist was 0.105 and 0.138. Inter-observer agreement was 0.204. Conclusion smr could become a tool for assessing CRM accurately." @default.
- W4213215300 created "2022-02-24" @default.
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- W4213215300 date "2019-12-30" @default.
- W4213215300 modified "2023-09-28" @default.
- W4213215300 title "Comparative Analysis of MRI and Pathological Findings in a Resected Specimen of Rectal Cancer" @default.
- W4213215300 doi "https://doi.org/10.21203/rs.2.19751/v1" @default.
- W4213215300 hasPublicationYear "2019" @default.
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