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- W4213216424 abstract "Genetics is believed to contribute to the etiology of almost every human trait and condition. For Mendelian disorders, such as sickle cell anemia, cystic fibrosis, establishing a role for genetics is straightforward. In reality, most genetic studies rely on clinic-based study populations because they provide the investigators with faster access to patients. The use of relative pairs has been a common ascertainment design in the genetic analysis of complex disorders. One of the characteristics of a genetic disorder is that it aggregates, or clusters, within families. Twin and adoption studies can be quite useful as they provide an opportunity to tease apart the role of genetics and a common familial environment. Adoption studies can also be used to examine the evidence for genetic versus common familial environmental factors. Heritability is a measurement of the genetic contribution to a trait, or how much of the trait variability can be attributed to genetics rather than other causes." @default.
- W4213216424 created "2022-02-24" @default.
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- W4213216424 date "2021-10-29" @default.
- W4213216424 modified "2023-09-27" @default.
- W4213216424 title "Determining the Genetic Component of a Disease" @default.
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- W4213216424 doi "https://doi.org/10.1002/9781119104100.ch3" @default.
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