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- W4213303466 abstract "The nanosized systems involving Pt(IV) complexes with antitumor activity are obtained by their solubilization via amphiphilic copolymers of N-vinylpyrrolidone and (di)methacrylates synthesized by the radical copolymerization in toluene without any polymer chain growth terminating agents. The resulting systems are investigated by a complex of physico-chemical methods (IR spectroscopy, DLS, TEM, cyclic and square-wave voltammetry) and quantum chemical simulation. The Pt(IV) complexes are shown to have cytotoxic effects on A-172 tumor cells and the corresponding cytotoxicity indices (IC50) are determined. The amphiphilic copolymers under consideration are promising modern platforms and delivery vehicles for biologically active compounds." @default.
- W4213303466 created "2022-02-24" @default.
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- W4213303466 date "2022-02-22" @default.
- W4213303466 modified "2023-09-25" @default.
- W4213303466 title "New Nanosized Systems with Antitumor Activity Based on the Pt(IV) Complexes with Nicotinamide Ligands and Amphiphilic Copolymers of N-Vinylpyrrolidone and (Di)methacrylate" @default.
- W4213303466 doi "https://doi.org/10.32931/io2123a" @default.
- W4213303466 hasPublicationYear "2022" @default.
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