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• W4213305053 abstract "Background: Outcome prognostication is still challenging in post-cardiac arrest patients although many methods have been introduced. Cerebral regional saturation of oxygen (crSO2) is one method that might relate to tissue viability, but its correlation with outcome of post-cardiac arrest patient remains unclear. We assessed the hypothesis that there might be significant correlation between the crSO2 level and the pre-cardiac arrest state and the prognosis of post-cardiac arrest patients. Methods: Adult post-cardiac arrest patients who received targeted temperature management (TTM) as our ICU protocol and who were under monitoring of frontal crSO2 by cerebral near-infrared spectroscopy (NIRS) were included. TTM was divided into phase 1 induction, phase 2 maintenance, and phase 3 rewarming. We recorded the value of frontal crSO2 every hour, and further data calculation (minimal, maximal, average, difference between phases) were done. Demographic and resuscitation variables, including pre-arrest CPC status were recorded. The primary outcome was the relation between crSO2 and mortality outcomes. The Mann-Whitney test was applied for analysis. Results: There were 28 post-cardiac arrest adult patients included since Nov. 2015 to Nov. 2017. In-hospital mortality rate were 53.6 % (15/28). For all patients, we found no significance between any crSO2 data of each phase and in-hospital mortality or neurological outcome when discharge. The median level of both side maximal average crSO2 at phase 3 in mortality group were 59 and was 62 in survival group, p= 0.354. Interestingly, the median level of both side maximal average crSO2 at phase 3 were 66 in the patients of pre-arrest CPC 1 and was 56 in pre-arrest CPC 2 (P=0.0328). In pre-arrest CPC 2 group, the both side maximal average crSO2 in phase 3 was significant lower in the in-hospital mortality group (median level 50 vs. 58, p=0.029). Conclusion: The crSO2 levels among different TTM phases were not significant correlated with mortality or neurological outcome. However, the pre-arrest CPC status may correlate with the crSO2. In patients with pre-arrest CPC 2, crSO2 had significant correlation with mortality. The crSO2 recorded by NIRS might be correlated to outcome in selected post-cardiac arrest patients." @default.
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• W4213305053 date "2018-11-06" @default.
• W4213305053 modified "2023-09-27" @default.
• W4213305053 title "Abstract 282: Relation Between the Post-Cardiac Arrest Cerebral Regional Saturation of Oxygen and Outcomes" @default.
• W4213305053 doi "https://doi.org/10.1161/circ.138.suppl_2.282" @default.
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