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- W4213305570 abstract "Heart failure (HF) is a major global healthcare problem accounting for substantial deterioration of prognosis. As a complex clinical syndrome, HF often coexists with multi-comorbidities of which cognitive impairment (CI) is particularly important. CI is increasing in prevalence among patients with HF and is present in around 40%, even up to 60%, of elderly patients with HF. As a potent and independent prognostic factor, CI significantly increases the hospitalization and mortality and decreases quality of life in patients with HF. There has been a growing awareness of the complex bidirectional interaction between HF and CI as it shares a number of common pathophysiological pathways including reduced cerebral blood flow, inflammation, and neurohumoral activations. Research that focus on the precise mechanism for CI in HF is still ever insufficient. As the tremendous adverse consequences of CI in HF, effective early diagnosis of CI in HF and interventions for these patients may halt disease progression and improve prognosis. The current clinical guidelines in HF have begun to emphasize the importance of CI. However, nearly half of CI in HF is underdiagnosed, and few recommendations are available to guide clinicians about how to approach CI in patients with HF. This review aims to synthesize knowledge about the link between HF and cognitive dysfunction, issues pertaining to screening, diagnosis and management of CI in patients with HF, and emerging therapies for prevention. Based on data from current studies, critical gaps in knowledge of CI in HF are identified, and future research directions to guide the field forward are proposed." @default.
- W4213305570 created "2022-02-24" @default.
- W4213305570 creator A5007957103 @default.
- W4213305570 creator A5029634597 @default.
- W4213305570 creator A5058328352 @default.
- W4213305570 creator A5064212066 @default.
- W4213305570 creator A5065369382 @default.
- W4213305570 creator A5066063008 @default.
- W4213305570 date "2022-02-07" @default.
- W4213305570 modified "2023-10-18" @default.
- W4213305570 title "Cognitive Impairment in Heart Failure: Landscape, Challenges, and Future Directions" @default.
- W4213305570 cites W1481903592 @default.
- W4213305570 cites W1489637646 @default.
- W4213305570 cites W1507743940 @default.
- W4213305570 cites W1719894433 @default.
- W4213305570 cites W181547059 @default.
- W4213305570 cites W1841850981 @default.
- W4213305570 cites W1847168837 @default.
- W4213305570 cites W1938819762 @default.
- W4213305570 cites W1970059419 @default.
- W4213305570 cites W1970695058 @default.
- W4213305570 cites W1972349970 @default.
- W4213305570 cites W1973484742 @default.
- W4213305570 cites W1973755223 @default.
- W4213305570 cites W1974948363 @default.
- W4213305570 cites W1975884974 @default.
- W4213305570 cites W1981785424 @default.
- W4213305570 cites W1986391730 @default.
- W4213305570 cites W1989796871 @default.
- W4213305570 cites W1992911798 @default.
- W4213305570 cites W1993064798 @default.
- W4213305570 cites W1993775827 @default.
- W4213305570 cites W1994761817 @default.
- W4213305570 cites W1997443192 @default.
- W4213305570 cites W2000004064 @default.
- W4213305570 cites W2002352560 @default.
- W4213305570 cites W2004513773 @default.
- W4213305570 cites W2007029142 @default.
- W4213305570 cites W2008854521 @default.
- W4213305570 cites W2011854877 @default.
- W4213305570 cites W2012022603 @default.
- W4213305570 cites W2019909629 @default.
- W4213305570 cites W2020822059 @default.
- W4213305570 cites W2022276867 @default.
- W4213305570 cites W2026914932 @default.
- W4213305570 cites W2027778296 @default.
- W4213305570 cites W2032122310 @default.
- W4213305570 cites W2043224889 @default.
- W4213305570 cites W2044002436 @default.
- W4213305570 cites W2044018155 @default.
- W4213305570 cites W2050291997 @default.
- W4213305570 cites W2052534047 @default.
- W4213305570 cites W2054031839 @default.
- W4213305570 cites W2054697757 @default.
- W4213305570 cites W2058161128 @default.
- W4213305570 cites W2059697135 @default.
- W4213305570 cites W2064148632 @default.
- W4213305570 cites W2066850127 @default.
- W4213305570 cites W2067541024 @default.
- W4213305570 cites W2068027072 @default.
- W4213305570 cites W2070272522 @default.
- W4213305570 cites W2071727563 @default.
- W4213305570 cites W2075275965 @default.
- W4213305570 cites W2077264199 @default.
- W4213305570 cites W2078027022 @default.
- W4213305570 cites W2082848310 @default.
- W4213305570 cites W2083163028 @default.
- W4213305570 cites W2084593700 @default.
- W4213305570 cites W2089355220 @default.
- W4213305570 cites W2093510859 @default.
- W4213305570 cites W2101090105 @default.
- W4213305570 cites W2101090291 @default.
- W4213305570 cites W2108475007 @default.
- W4213305570 cites W2109527205 @default.
- W4213305570 cites W2112986223 @default.
- W4213305570 cites W2114624908 @default.
- W4213305570 cites W2124779892 @default.
- W4213305570 cites W2127791111 @default.
- W4213305570 cites W2128854403 @default.
- W4213305570 cites W2133415315 @default.
- W4213305570 cites W2136693607 @default.
- W4213305570 cites W2139192063 @default.
- W4213305570 cites W2139229973 @default.
- W4213305570 cites W2141176548 @default.
- W4213305570 cites W2143933390 @default.
- W4213305570 cites W2145173243 @default.
- W4213305570 cites W2146967348 @default.
- W4213305570 cites W2148080316 @default.
- W4213305570 cites W2153692392 @default.
- W4213305570 cites W2154900811 @default.
- W4213305570 cites W2155152361 @default.
- W4213305570 cites W2157813392 @default.
- W4213305570 cites W2159122349 @default.
- W4213305570 cites W2165758561 @default.
- W4213305570 cites W2167311298 @default.
- W4213305570 cites W2168610467 @default.
- W4213305570 cites W2172145526 @default.
- W4213305570 cites W2209399555 @default.
- W4213305570 cites W2254797072 @default.
- W4213305570 cites W2276853091 @default.