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- W4213305981 abstract "This review contextualizes the collective research on in situ proton postmortem magnetic resonance spectroscopy of the brain and derives the basic approaches for its application in forensic pathology. The basic concepts of magnetic resonance spectroscopy are outlined for a target audience in forensic pathology. A major application of postmortem in situ magnetic resonance spectroscopy is the prediction of the postmortem interval, which has been demonstrated in animal studies. Current research has directly quantified relevant metabolites such as ethanol, glucose, and beta-hydroxybutyrate to draw conclusions for forensic casework. This application is currently limited to a few relevant metabolites. A future potential of postmortem in situ magnetic resonance spectroscopy is the analysis of the entire metabolomic pattern. Estimation of cause of death based on the postmortem metabolome could be the next milestone in postmortem in situ magnetic resonance spectroscopy." @default.
- W4213305981 created "2022-02-24" @default.
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- W4213305981 date "2022-06-01" @default.
- W4213305981 modified "2023-09-27" @default.
- W4213305981 title "Fundamentals of in situ postmortem magnetic resonance spectroscopy of the brain in the forensic framework - a review and outlook" @default.
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- W4213305981 doi "https://doi.org/10.1016/j.fri.2022.200499" @default.
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