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• W4213364787 abstract "COVID 19 was characterized as a pandemic by the WHO since march 2020.peoples all over the world suffered from this infection but patients with chronic diseases such as kidney impairment were seriously affected. Moreover, a varied pattern of kidney injury was described with COVID 19.the purpose of our study was to relate demographic, clinical and biological features in patients infected by the SARS-Cov 2 and referred either to our nephrology department or hemodialysis (HD) center. We retrospectively collected data about patients with a nephrologic matter, who suffered from COVID 19 between October 2020 and march 2021. 100 patients were included.54% were men and 46% were women. The mean age of the patients was 59.55±15.5 years.63% were hospitalized and the others were dialyzed in our HD unity. 5% of the hospitalized patients experienced a severe form and were admitted in the nephrology intensive care unit.40% were diabetic and 55% were hypertensive.21% had a cardiopathy and 81% had a chronic kidney disease. Among them 47% were on HD ,7% were transplanted and one patient received peritoneal dialysis.29% were obese and 4% were active smoker. A positive contact tracing with a COVID 19 confirmed case was found in 43% of cases. As for Clinical severity of the infection:18% of our patients had no symptoms,40% had a mild infection ,19% had a moderate disease and 23% had unfortunately a severe form. The most frequent symptoms were respectively: asthenia (47%), fever (43%), dry cough (43%), dyspnea (43%), diarrhea (25%) and arthro-myalgia (19%). The profile of kidney impairment occurred within SARS Cov2 infection was as follow: acute kidney injury in 11%, altered chronic renal function in 23%, hematuria in 3.2% and proteinuria in 6.4% of all cases. main laboratory findings were lymphopenia (38%), lactate dehydrogenase elevation (46%), metabolic acidosis (36%), hypoalbuminemia (21%), hyponatremia (16%), hyperkaliemia (16%), low prothrombin time (11%). CT Scan imaging of the chest showed mild lung injury in 25%, moderate lung injury in 27% and severe lung injury in 20% of all patients. The main pejorative outcomes noted were: respiratory bacterial superinfection (19%), hemophagocytic lymphohistiocytosis (6%) and acute severe respiratory syndrome (5%). finally,88% of our patients had a global favorable outcome and were discharged from hospital but unfortunately 12% died. According to our study, demographic and clinical characteristics of nephrologic patients seems to be similar to the general population but they may be more exposed to serious outcomes especially death." @default.
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• W4213364787 date "2022-02-01" @default.
• W4213364787 modified "2023-10-18" @default.
• W4213364787 title "POS-888 COVID 19 PATIENTS WITH A NEPHROLOGIC CONCERN: A DESCRIPTIVE STUDY FROM A SINGLE CENTER IN TUNISIA" @default.
• W4213364787 doi "https://doi.org/10.1016/j.ekir.2022.01.927" @default.
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