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- W4213371000 abstract "Abstract Background The previous study found that the Jinlida could significantly reduce levels of blood glucose and enhance the lowing-glucose action of metformin. However, the role of the standard-reaching rate of blood glucose and improving clinical symptoms in Jinlida has yet to be studied. We aimed to elaborate on the efficacy of Jinlida in Type 2 diabetics who experience clinical symptoms based on secondary analysis from the 12-week trial. Methods Data were analyzed from a 12-week, randomized, placebo-controlled, study of Jinlida. The standard-reaching rate of blood glucose, total symptom score, the efficacy of single symptom, symptom disappearance rate, symptom improvement rate was evaluated. Then, the correlation of the symptom effective rate and HbA1c was analyzed. Results 192 T2DM patients were randomly allocated to receive either Jinlida or a placebo for 12 consecutive weeks. The standard-reaching rate of HbA1c (<6.5%) was 25% in the treatment group when compared to 14.9% in the control group. (P=0.046); All the symptom exhibited a change difference, comparing the treatment group to the control group after 12 weeks’ intervention. (P< 0.05); Hunger, polyuria, dry mouth, sweating and dysphoria in chestpalms-soles symptoms exhibited a change difference in the treatment group, compared to that in the control group. (P<0.05). All the symptom exhibited a significant difference in symptom improvement rate. (P<0.05). Conclusions Jinlida glandule can effectively improve clinical symptoms of type 2 diabetics including thirsty, fatigue, hunger, polyuria, dry mouth, night-sweat, dysphoria in chenstplms-soles and constipation. It can be used as an effective adjuvant treatment for T2DM who experience those symptoms. However, these findings need to be further confirmed by evidence-based medicine." @default.
- W4213371000 created "2022-02-24" @default.
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- W4213371000 date "2021-12-13" @default.
- W4213371000 modified "2023-09-25" @default.
- W4213371000 title "Evaluation of Jinlida Granules in Improvements to Standard-Reaching Rate of Blood Glucose and Type 2 Diabetes Mellitus Symptoms: Results of Secondary Analysis From 12-Week Trial" @default.
- W4213371000 doi "https://doi.org/10.21203/rs.3.rs-1146252/v1" @default.
- W4213371000 hasPublicationYear "2021" @default.
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