Matches in SemOpenAlex for { <https://semopenalex.org/work/W4213426315> ?p ?o ?g. }
- W4213426315 endingPage "127" @default.
- W4213426315 startingPage "118" @default.
- W4213426315 abstract "Myocardial injury in COVID-19 is associated with in-hospital mortality. However, the development of myocardial injury over time and whether myocardial injury in patients with COVID-19 at the intensive care unit is associated with outcome is unclear. This study prospectively investigates myocardial injury with serial measurements over the full course of intensive care unit admission in mechanically ventilated patients with COVID-19. As part of the prospective Maastricht Intensive Care COVID cohort, predefined myocardial injury markers, including high-sensitivity cardiac troponin T (hs-cTnT), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and electrocardiographic characteristics were serially collected in mechanically ventilated patients with COVID-19. Linear mixed-effects regression was used to compare survivors with nonsurvivors, adjusting for gender, age, APACHE-II score, daily creatinine concentration, hypertension, diabetes mellitus, and obesity. In 90 patients, 57 (63%) were survivors and 33 (37%) nonsurvivors, and a total of 628 serial electrocardiograms, 1,565 hs-cTnT, and 1,559 NT-proBNP concentrations were assessed. Log-hs-cTnT was lower in survivors compared with nonsurvivors at day 1 (β -0.93 [-1.37; -0.49], p <0.001) and did not change over time. Log-NT-proBNP did not differ at day 1 between both groups but decreased over time in the survivor group (β -0.08 [-0.11; -0.04] p <0.001) compared with nonsurvivors. Many electrocardiographic abnormalities were present in the whole population, without significant differences between both groups. In conclusion, baseline hs-cTnT and change in NT-proBNP were strongly associated with mortality. Two-thirds of patients with COVID-19 showed electrocardiographic abnormalities. Our serial assessment suggests that myocardial injury is common in mechanically ventilated patients with COVID-19 and is associated with outcome." @default.
- W4213426315 created "2022-02-25" @default.
- W4213426315 creator A5007311987 @default.
- W4213426315 creator A5007336328 @default.
- W4213426315 creator A5019121576 @default.
- W4213426315 creator A5028712821 @default.
- W4213426315 creator A5033298453 @default.
- W4213426315 creator A5033655582 @default.
- W4213426315 creator A5048637744 @default.
- W4213426315 creator A5049901772 @default.
- W4213426315 creator A5056785549 @default.
- W4213426315 creator A5058117174 @default.
- W4213426315 creator A5074000342 @default.
- W4213426315 creator A5074434790 @default.
- W4213426315 creator A5086740589 @default.
- W4213426315 creator A5086752339 @default.
- W4213426315 date "2022-05-01" @default.
- W4213426315 modified "2023-09-26" @default.
- W4213426315 title "Serial Assessment of Myocardial Injury Markers in Mechanically Ventilated Patients With SARS-CoV-2 (from the Prospective MaastrICCht Cohort)" @default.
- W4213426315 cites W2017086716 @default.
- W4213426315 cites W2025672718 @default.
- W4213426315 cites W2163866651 @default.
- W4213426315 cites W2944687799 @default.
- W4213426315 cites W3007878828 @default.
- W4213426315 cites W3007940623 @default.
- W4213426315 cites W3009976289 @default.
- W4213426315 cites W3012747666 @default.
- W4213426315 cites W3013231340 @default.
- W4213426315 cites W3013785240 @default.
- W4213426315 cites W3013949914 @default.
- W4213426315 cites W3014571869 @default.
- W4213426315 cites W3015731395 @default.
- W4213426315 cites W3036495743 @default.
- W4213426315 cites W3049206116 @default.
- W4213426315 cites W3086411487 @default.
- W4213426315 cites W3091459927 @default.
- W4213426315 cites W3092776109 @default.
- W4213426315 cites W3102371316 @default.
- W4213426315 cites W3123312433 @default.
- W4213426315 cites W3137300335 @default.
- W4213426315 cites W3137597435 @default.
- W4213426315 cites W3155872674 @default.
- W4213426315 cites W3162739727 @default.
- W4213426315 cites W3162905796 @default.
- W4213426315 cites W3165656738 @default.
- W4213426315 cites W4230914943 @default.
- W4213426315 cites W4292229870 @default.
- W4213426315 doi "https://doi.org/10.1016/j.amjcard.2022.01.030" @default.
- W4213426315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35221103" @default.
- W4213426315 hasPublicationYear "2022" @default.
- W4213426315 type Work @default.
- W4213426315 citedByCount "4" @default.
- W4213426315 countsByYear W42134263152022 @default.
- W4213426315 countsByYear W42134263152023 @default.
- W4213426315 crossrefType "journal-article" @default.
- W4213426315 hasAuthorship W4213426315A5007311987 @default.
- W4213426315 hasAuthorship W4213426315A5007336328 @default.
- W4213426315 hasAuthorship W4213426315A5019121576 @default.
- W4213426315 hasAuthorship W4213426315A5028712821 @default.
- W4213426315 hasAuthorship W4213426315A5033298453 @default.
- W4213426315 hasAuthorship W4213426315A5033655582 @default.
- W4213426315 hasAuthorship W4213426315A5048637744 @default.
- W4213426315 hasAuthorship W4213426315A5049901772 @default.
- W4213426315 hasAuthorship W4213426315A5056785549 @default.
- W4213426315 hasAuthorship W4213426315A5058117174 @default.
- W4213426315 hasAuthorship W4213426315A5074000342 @default.
- W4213426315 hasAuthorship W4213426315A5074434790 @default.
- W4213426315 hasAuthorship W4213426315A5086740589 @default.
- W4213426315 hasAuthorship W4213426315A5086752339 @default.
- W4213426315 hasBestOaLocation W42134263151 @default.
- W4213426315 hasConcept C126322002 @default.
- W4213426315 hasConcept C144469398 @default.
- W4213426315 hasConcept C164705383 @default.
- W4213426315 hasConcept C177713679 @default.
- W4213426315 hasConcept C188816634 @default.
- W4213426315 hasConcept C2775915353 @default.
- W4213426315 hasConcept C2776376669 @default.
- W4213426315 hasConcept C2778198053 @default.
- W4213426315 hasConcept C2908647359 @default.
- W4213426315 hasConcept C2987404301 @default.
- W4213426315 hasConcept C36036425 @default.
- W4213426315 hasConcept C500558357 @default.
- W4213426315 hasConcept C71924100 @default.
- W4213426315 hasConcept C72563966 @default.
- W4213426315 hasConcept C8880881 @default.
- W4213426315 hasConcept C99454951 @default.
- W4213426315 hasConceptScore W4213426315C126322002 @default.
- W4213426315 hasConceptScore W4213426315C144469398 @default.
- W4213426315 hasConceptScore W4213426315C164705383 @default.
- W4213426315 hasConceptScore W4213426315C177713679 @default.
- W4213426315 hasConceptScore W4213426315C188816634 @default.
- W4213426315 hasConceptScore W4213426315C2775915353 @default.
- W4213426315 hasConceptScore W4213426315C2776376669 @default.
- W4213426315 hasConceptScore W4213426315C2778198053 @default.
- W4213426315 hasConceptScore W4213426315C2908647359 @default.
- W4213426315 hasConceptScore W4213426315C2987404301 @default.
- W4213426315 hasConceptScore W4213426315C36036425 @default.
- W4213426315 hasConceptScore W4213426315C500558357 @default.