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- W4213427596 abstract "This chapter describes basic principles and key findings regarding the development and maturation of the human brain, the former referring to the pre-natal and early post-natal periods, and the latter concerning childhood and adolescence. In both cases, we focus on brain structure as revealed in vivo with multi-modal magnetic resonance imaging (MRI). We begin with a few numbers about the human brain and its cellular composition, and a brief overview of a number of MRI-based metrics used to characterize age-related variations in grey and white matter. We then proceed with synthesizing current knowledge about developmental and maturational changes in the cerebral cortex (its thickness, surface area and intra-cortical myelination), and the underlying white matter (volume and structural properties). To facilitate biological interpretations of MRI-derived metrics, we introduce the concept of virtual histology. We conclude the chapter with a few notes about future directions in the study of factors shaping the human brain from conception onwards." @default.
- W4213427596 created "2022-02-25" @default.
- W4213427596 creator A5008874281 @default.
- W4213427596 date "2022-02-28" @default.
- W4213427596 modified "2023-10-17" @default.
- W4213427596 title "Development and Maturation of the Human Brain, from Infancy to Adolescence" @default.
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- W4213427596 doi "https://doi.org/10.1017/9781108399838.006" @default.
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