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- W4213428178 abstract "Site-specific delivery of antibiotics has always been a high-priority area in pharmaceutical research. Conventionally used antibiotics suffer several limitations, such as low accumulation and penetration in diseased cells/tissues, limited bioavailability of drugs, drug resistance, and off-target toxicity. To overcome these limitations, several strategies have been exploited for delivering antibiotics to the site of infection, such as the use of stimuli-responsive antibiotic delivery systems, which can release antibiotics in a controlled and timely fashion. These stimuli can either be exogenous (light, magnetism, ultrasound, and electrical) or endogenous (pH, redox reactions, and enzymatic). In this review, we present a summary of recent developments in the field of stimuli-based targeted drug delivery systems for the site-specific release of antibiotics." @default.
- W4213428178 created "2022-02-25" @default.
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- W4213428178 date "2022-06-01" @default.
- W4213428178 modified "2023-10-18" @default.
- W4213428178 title "Stimuli-sensitive drug delivery systems for site-specific antibiotic release" @default.
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- W4213428178 doi "https://doi.org/10.1016/j.drudis.2022.02.014" @default.
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