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- W4213455153 abstract "Chiral phosphine-containing skeletons are important motifs in bioactive natural products, pharmaceuticals, chiral catalysts, and ligands. Herein, we report a general and modular platform to access chiral α-aryl phosphorus compounds via a Ni/photoredox-catalyzed enantioconvergent reductive cross-coupling between α-bromophosphates and aryl iodides. This dual catalytic regime exhibited high efficiency and good functional group compacity. A wide variety of substrates bearing a diverse set of functional groups could be converted into chiral phosphates in good to excellent yields and enantioselectivities. The utility of the method was also demonstrated by the development of a new phosphine ligand and the synthesis of enzyme inhibitor derivatives. The detailed mechanistic studies supported a radical chain process and revealed a unique distinction compared with traditional reductive cross-coupling." @default.
- W4213455153 created "2022-02-25" @default.
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- W4213455153 creator A5076312131 @default.
- W4213455153 creator A5083220859 @default.
- W4213455153 date "2022-02-22" @default.
- W4213455153 modified "2023-10-16" @default.
- W4213455153 title "Modular and Facile Access to Chiral α-Aryl Phosphates via Dual Nickel- and Photoredox-Catalyzed Reductive Cross-Coupling" @default.
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- W4213455153 cites W1995833331 @default.
- W4213455153 cites W2015005155 @default.
- W4213455153 cites W2042082239 @default.
- W4213455153 cites W2051822378 @default.
- W4213455153 cites W2057469573 @default.
- W4213455153 cites W2060479278 @default.
- W4213455153 cites W2066243266 @default.
- W4213455153 cites W2077657121 @default.
- W4213455153 cites W2118124919 @default.
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- W4213455153 cites W2258822168 @default.
- W4213455153 cites W2274216513 @default.
- W4213455153 cites W2278002274 @default.
- W4213455153 cites W2313863596 @default.
- W4213455153 cites W2318384131 @default.
- W4213455153 cites W2342398197 @default.
- W4213455153 cites W2401988800 @default.
- W4213455153 cites W2466522572 @default.
- W4213455153 cites W2468940798 @default.
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- W4213455153 doi "https://doi.org/10.1021/jacs.1c12424" @default.
- W4213455153 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35192328" @default.
- W4213455153 hasPublicationYear "2022" @default.
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