Matches in SemOpenAlex for { <https://semopenalex.org/work/W4213459161> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W4213459161 abstract "ATP synthase is a membrane-bound rotary motor enzyme that is critical for cellular energy metabolism in all kingdoms of life. Despite conservation of its basic structure and function, autoinhibition by one of its rotary stalk subunits occurs in bacteria and chloroplasts but not in mitochondria. The crystal structure of the ATP synthase catalytic complex (F(1)) from Escherichia coli described here reveals the structural basis for this inhibition. The C-terminal domain of subunit ɛ adopts a heretofore unknown, highly extended conformation that inserts deeply into the central cavity of the enzyme and engages both rotor and stator subunits in extensive contacts that are incompatible with functional rotation. As a result, the three catalytic subunits are stabilized in a set of conformations and rotational positions distinct from previous F(1) structures. PMID: 21602818 Funding information This work was supported by: NIGMS NIH HHS, United States Grant ID: R01GM083088 NIGMS NIH HHS, United States Grant ID: R01 GM083088-02 NIGMS NIH HHS, United States Grant ID: R01 GM083088" @default.
- W4213459161 created "2022-02-25" @default.
- W4213459161 creator A5073195037 @default.
- W4213459161 creator A5085637404 @default.
- W4213459161 date "2011-06-13" @default.
- W4213459161 modified "2023-09-26" @default.
- W4213459161 title "Faculty Opinions recommendation of Structure of the ATP synthase catalytic complex (F(1)) from Escherichia coli in an autoinhibited conformation." @default.
- W4213459161 doi "https://doi.org/10.3410/f.10864956.12211056" @default.
- W4213459161 hasPublicationYear "2011" @default.
- W4213459161 type Work @default.
- W4213459161 citedByCount "0" @default.
- W4213459161 crossrefType "dataset" @default.
- W4213459161 hasAuthorship W4213459161A5073195037 @default.
- W4213459161 hasAuthorship W4213459161A5085637404 @default.
- W4213459161 hasBestOaLocation W42134591611 @default.
- W4213459161 hasConcept C104292427 @default.
- W4213459161 hasConcept C104317684 @default.
- W4213459161 hasConcept C112243037 @default.
- W4213459161 hasConcept C119120687 @default.
- W4213459161 hasConcept C141315368 @default.
- W4213459161 hasConcept C181199279 @default.
- W4213459161 hasConcept C185592680 @default.
- W4213459161 hasConcept C23265538 @default.
- W4213459161 hasConcept C547475151 @default.
- W4213459161 hasConcept C55493867 @default.
- W4213459161 hasConcept C71240020 @default.
- W4213459161 hasConcept C8010536 @default.
- W4213459161 hasConcept C86803240 @default.
- W4213459161 hasConceptScore W4213459161C104292427 @default.
- W4213459161 hasConceptScore W4213459161C104317684 @default.
- W4213459161 hasConceptScore W4213459161C112243037 @default.
- W4213459161 hasConceptScore W4213459161C119120687 @default.
- W4213459161 hasConceptScore W4213459161C141315368 @default.
- W4213459161 hasConceptScore W4213459161C181199279 @default.
- W4213459161 hasConceptScore W4213459161C185592680 @default.
- W4213459161 hasConceptScore W4213459161C23265538 @default.
- W4213459161 hasConceptScore W4213459161C547475151 @default.
- W4213459161 hasConceptScore W4213459161C55493867 @default.
- W4213459161 hasConceptScore W4213459161C71240020 @default.
- W4213459161 hasConceptScore W4213459161C8010536 @default.
- W4213459161 hasConceptScore W4213459161C86803240 @default.
- W4213459161 hasLocation W42134591611 @default.
- W4213459161 hasOpenAccess W4213459161 @default.
- W4213459161 hasPrimaryLocation W42134591611 @default.
- W4213459161 hasRelatedWork W150994682 @default.
- W4213459161 hasRelatedWork W1521333523 @default.
- W4213459161 hasRelatedWork W1966393377 @default.
- W4213459161 hasRelatedWork W1977355543 @default.
- W4213459161 hasRelatedWork W1982113491 @default.
- W4213459161 hasRelatedWork W1996986950 @default.
- W4213459161 hasRelatedWork W2016089022 @default.
- W4213459161 hasRelatedWork W2375649700 @default.
- W4213459161 hasRelatedWork W2414657539 @default.
- W4213459161 hasRelatedWork W2809277775 @default.
- W4213459161 isParatext "false" @default.
- W4213459161 isRetracted "false" @default.
- W4213459161 workType "dataset" @default.