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• W4214489004 endingPage "32" @default.
• W4214489004 startingPage "32" @default.
• W4214489004 abstract "Subretinal drusenoid deposits (SDD) first appear in the rod-rich perifovea and can extend to the cone-rich fovea. To refine the spatial relationship of visual dysfunction with SDD burden, we determined the topography of mesopic and scotopic light sensitivity in participants with non-neovascular AMD with and without SDD.Thirty-three subjects were classified into three groups: normal (n = 9), AMD-Drusen (with drusen and without SDD; n = 12), and AMD-SDD (predominantly SDD; n = 12). Mesopic and scotopic microperimetry were performed using 68 targets within the Early Treatment Diabetic Retinopathy Study grid, including points at 1.7° from the foveal center (rod:cone ratio, 0.35). Age-adjusted linear regression was used to compare mesopic and scotopic light sensitivities across groups.Across the entire Early Treatment Diabetic Retinopathy Study grid and within individual subfields, the three groups differed significantly for mesopic and scotopic light sensitivities (all P < 0.05). The AMD-SDD group exhibited significantly decreased mesopic and scotopic sensitivity versus both the normal and the AMD-Drusen groups (all P < 0.05), while AMD-Drusen and normal eyes did not significantly differ (all P > 0.05). The lowest relative sensitivities were recorded for scotopic light levels, especially in the central subfield, in the AMD-SDD group.SDD-associated decrements in rod-mediated vision can be detected close to the foveola, and these deficits are proportionately worse than functional loss in the rod-rich perifovea. This finding suggests that factors other than the previously hypothesized direct cytotoxicity to photoreceptors and local transport barrier limitations may negatively impact vision. Larger prospective studies are required to confirm these observations." @default.
• W4214489004 created "2022-03-02" @default.
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• W4214489004 date "2022-02-25" @default.
• W4214489004 modified "2023-10-14" @default.
• W4214489004 title "Spatial Dissociation of Subretinal Drusenoid Deposits and Impaired Scotopic and Mesopic Sensitivity in AMD" @default.
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• W4214489004 cites W1547554564 @default.
• W4214489004 cites W1577290027 @default.
• W4214489004 cites W159419684 @default.
• W4214489004 cites W1607067213 @default.
• W4214489004 cites W183849934 @default.
• W4214489004 cites W1853674701 @default.
• W4214489004 cites W1877983131 @default.
• W4214489004 cites W1970140546 @default.
• W4214489004 cites W1973652650 @default.
• W4214489004 cites W1991661185 @default.
• W4214489004 cites W1993969132 @default.
• W4214489004 cites W1996821302 @default.
• W4214489004 cites W2002611540 @default.
• W4214489004 cites W2002969780 @default.
• W4214489004 cites W2011845506 @default.
• W4214489004 cites W2023886778 @default.
• W4214489004 cites W2024016853 @default.
• W4214489004 cites W2025979869 @default.
• W4214489004 cites W2040209050 @default.
• W4214489004 cites W2045011938 @default.
• W4214489004 cites W2048088899 @default.
• W4214489004 cites W2062160894 @default.
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• W4214489004 cites W2133061104 @default.
• W4214489004 cites W2171855270 @default.
• W4214489004 cites W2320696053 @default.
• W4214489004 cites W2333335636 @default.
• W4214489004 cites W2346856078 @default.
• W4214489004 cites W2415316977 @default.
• W4214489004 cites W2419123448 @default.
• W4214489004 cites W2523178255 @default.
• W4214489004 cites W2535783572 @default.
• W4214489004 cites W2548952825 @default.
• W4214489004 cites W2619171481 @default.
• W4214489004 cites W2621359636 @default.
• W4214489004 cites W2734931180 @default.
• W4214489004 cites W2735344948 @default.
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• W4214489004 cites W2898549572 @default.
• W4214489004 cites W2898580429 @default.
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• W4214489004 cites W2938857728 @default.
• W4214489004 cites W2954233568 @default.
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• W4214489004 cites W2979815385 @default.
• W4214489004 cites W2988969159 @default.
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• W4214489004 cites W3005516510 @default.
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• W4214489004 doi "https://doi.org/10.1167/iovs.63.2.32" @default.
• W4214489004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35212721" @default.
• W4214489004 hasPublicationYear "2022" @default.
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