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- W4214496048 endingPage "100808" @default.
- W4214496048 startingPage "100808" @default.
- W4214496048 abstract "Nanoparticle-based therapeutics have been applied in a broad range of clinical and preclinical applications from diagnosis to treatment for cancer. A wide range of synthetic and naturally occurring materials, such as polymers, metal oxides, silicate, liposomes, and carbon nanotubes, have been developed to overcome key barriers in small molecule therapeutics, including intracellular trafficking, cell/tissue targeting, poor biodistribution, and low efficiency. Virus-like particles—engineered and non-infectious self-assembling systems based on viral nanostructures—are new approach toward overcoming these limitations, as they are a protein-based nanomaterial that closely mimics the highly symmetrical and polyvalent conformation of viruses while lacking the viral genomes. Their innate biocompatibility, biodegradability, monodispersity, mild immunogenicity, and safety combined with the capacity to chemically modify the interior and exterior surfaces of these systems offer scientists a highly customizable tool to design and engineer multicomponent therapeutic agents. In this review, we discuss how these systems have been used in a wide array of cancer treatments, including phototherapy, immunotherapy, gene therapy, and chemotherapy." @default.
- W4214496048 created "2022-03-02" @default.
- W4214496048 creator A5042763588 @default.
- W4214496048 creator A5045936532 @default.
- W4214496048 creator A5051702071 @default.
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- W4214496048 creator A5080632531 @default.
- W4214496048 creator A5083031165 @default.
- W4214496048 creator A5086850002 @default.
- W4214496048 date "2022-06-01" @default.
- W4214496048 modified "2023-10-16" @default.
- W4214496048 title "Virus-like particles: a self-assembled toolbox for cancer therapy" @default.
- W4214496048 cites W1483641353 @default.
- W4214496048 cites W1517917113 @default.
- W4214496048 cites W1601821153 @default.
- W4214496048 cites W1606853210 @default.
- W4214496048 cites W1671075316 @default.
- W4214496048 cites W1840940599 @default.
- W4214496048 cites W1903406597 @default.
- W4214496048 cites W1937217752 @default.
- W4214496048 cites W1964275463 @default.
- W4214496048 cites W1965767348 @default.
- W4214496048 cites W1966225171 @default.
- W4214496048 cites W1969571696 @default.
- W4214496048 cites W1970318791 @default.
- W4214496048 cites W1971129537 @default.
- W4214496048 cites W1972869225 @default.
- W4214496048 cites W1986020552 @default.
- W4214496048 cites W1988505882 @default.
- W4214496048 cites W1991701295 @default.
- W4214496048 cites W1993367761 @default.
- W4214496048 cites W2000319267 @default.
- W4214496048 cites W2005289647 @default.
- W4214496048 cites W2011364697 @default.
- W4214496048 cites W2011399997 @default.
- W4214496048 cites W2017936375 @default.
- W4214496048 cites W2019338935 @default.
- W4214496048 cites W2020719323 @default.
- W4214496048 cites W2020908290 @default.
- W4214496048 cites W2026465936 @default.
- W4214496048 cites W2029466014 @default.
- W4214496048 cites W2034383333 @default.
- W4214496048 cites W2037221129 @default.
- W4214496048 cites W2039472971 @default.
- W4214496048 cites W2041299640 @default.
- W4214496048 cites W2044072446 @default.
- W4214496048 cites W2046182783 @default.
- W4214496048 cites W2051031007 @default.
- W4214496048 cites W2051714526 @default.
- W4214496048 cites W2053795281 @default.
- W4214496048 cites W2054949003 @default.
- W4214496048 cites W2056915350 @default.
- W4214496048 cites W2061182551 @default.
- W4214496048 cites W2062061048 @default.
- W4214496048 cites W2075415955 @default.
- W4214496048 cites W2078964476 @default.
- W4214496048 cites W2083453090 @default.
- W4214496048 cites W2085048677 @default.
- W4214496048 cites W2107898312 @default.
- W4214496048 cites W2116732852 @default.
- W4214496048 cites W2121897407 @default.
- W4214496048 cites W2127782698 @default.
- W4214496048 cites W2130163947 @default.
- W4214496048 cites W2139107535 @default.
- W4214496048 cites W2142897044 @default.
- W4214496048 cites W2148284816 @default.
- W4214496048 cites W2149407868 @default.
- W4214496048 cites W2149913957 @default.
- W4214496048 cites W2152863535 @default.
- W4214496048 cites W2154203858 @default.
- W4214496048 cites W2156801977 @default.
- W4214496048 cites W2162148353 @default.
- W4214496048 cites W2167284803 @default.
- W4214496048 cites W2255455792 @default.
- W4214496048 cites W2271755367 @default.
- W4214496048 cites W2278726896 @default.
- W4214496048 cites W2284745064 @default.
- W4214496048 cites W2294780803 @default.
- W4214496048 cites W2297943438 @default.
- W4214496048 cites W2302172313 @default.
- W4214496048 cites W2316459203 @default.
- W4214496048 cites W2327604072 @default.
- W4214496048 cites W2361469323 @default.
- W4214496048 cites W2551840286 @default.
- W4214496048 cites W2561278972 @default.
- W4214496048 cites W2562690513 @default.
- W4214496048 cites W2591848333 @default.
- W4214496048 cites W2593353853 @default.
- W4214496048 cites W2598119627 @default.
- W4214496048 cites W2604084092 @default.
- W4214496048 cites W2613355878 @default.
- W4214496048 cites W2616129231 @default.
- W4214496048 cites W2626547112 @default.
- W4214496048 cites W2657735424 @default.
- W4214496048 cites W2743604908 @default.
- W4214496048 cites W2747015363 @default.
- W4214496048 cites W2754140940 @default.
- W4214496048 cites W2755387723 @default.