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- W4214519984 abstract "Melatonin is the primary hormone of the pineal gland that is secreted at night. It regulates many physiological functions, including the sleep-wake cycle, gonadal activity, free radical scavenging, immunomodulation, neuro-protection, and cancer progression. The precise functions of melatonin are mediated by guanosine triphosphate (GTP)-binding protein (G-protein) coupled melatonin receptor 1 (MT1) and MT2 receptors. However, nuclear receptors are also associated with melatonin activity. Circadian rhythm disruption, shift work, and light exposure at night hamper melatonin production. Impaired melatonin level promotes various pathophysiological changes, including cancer. In our modern society, breast cancer is a serious problem throughout the world. Several studies have been indicated the link between low levels of melatonin and breast cancer development. Melatonin has oncostatic properties in breast cancer cells. This indolamine advances apoptosis, which arrests the cell cycle and regulates metabolic activity. Moreover, melatonin increases the treatment efficacy of cancer and can be used as an adjuvant with chemotherapeutic agents." @default.
- W4214519984 created "2022-03-02" @default.
- W4214519984 creator A5020986485 @default.
- W4214519984 creator A5048814223 @default.
- W4214519984 date "2022-02-25" @default.
- W4214519984 modified "2023-09-30" @default.
- W4214519984 title "The potential anti-cancer effects of melatonin on breast cancer" @default.
- W4214519984 cites W114098355 @default.
- W4214519984 cites W1504765440 @default.
- W4214519984 cites W1538008426 @default.
- W4214519984 cites W1549140675 @default.
- W4214519984 cites W1622456520 @default.
- W4214519984 cites W1847108160 @default.
- W4214519984 cites W1964187078 @default.
- W4214519984 cites W1966342316 @default.
- W4214519984 cites W1973703381 @default.
- W4214519984 cites W1978978516 @default.
- W4214519984 cites W1985050692 @default.
- W4214519984 cites W1992479606 @default.
- W4214519984 cites W1993826373 @default.
- W4214519984 cites W2008588675 @default.
- W4214519984 cites W2012901315 @default.
- W4214519984 cites W2015127357 @default.
- W4214519984 cites W2019384027 @default.
- W4214519984 cites W2020031354 @default.
- W4214519984 cites W2021607553 @default.
- W4214519984 cites W2024482156 @default.
- W4214519984 cites W2024536570 @default.
- W4214519984 cites W2026338152 @default.
- W4214519984 cites W2026605955 @default.
- W4214519984 cites W2028122342 @default.
- W4214519984 cites W2031921473 @default.
- W4214519984 cites W2039590429 @default.
- W4214519984 cites W2040145088 @default.
- W4214519984 cites W2045257104 @default.
- W4214519984 cites W2047296832 @default.
- W4214519984 cites W2048617897 @default.
- W4214519984 cites W2065813249 @default.
- W4214519984 cites W2066450536 @default.
- W4214519984 cites W2070727232 @default.
- W4214519984 cites W2079376223 @default.
- W4214519984 cites W2080191063 @default.
- W4214519984 cites W2087366979 @default.
- W4214519984 cites W2090310668 @default.
- W4214519984 cites W2090740247 @default.
- W4214519984 cites W2095051743 @default.
- W4214519984 cites W2097919146 @default.
- W4214519984 cites W2106497761 @default.
- W4214519984 cites W2114936576 @default.
- W4214519984 cites W2115908598 @default.
- W4214519984 cites W2120854324 @default.
- W4214519984 cites W2121897465 @default.
- W4214519984 cites W2127465976 @default.
- W4214519984 cites W2127500797 @default.
- W4214519984 cites W2136429046 @default.
- W4214519984 cites W2139578633 @default.
- W4214519984 cites W2145811831 @default.
- W4214519984 cites W2151132444 @default.
- W4214519984 cites W2158229562 @default.
- W4214519984 cites W2161356385 @default.
- W4214519984 cites W2169348314 @default.
- W4214519984 cites W2223535266 @default.
- W4214519984 cites W2308891651 @default.
- W4214519984 cites W2323939601 @default.
- W4214519984 cites W2479507898 @default.
- W4214519984 cites W2493364917 @default.
- W4214519984 cites W2517129379 @default.
- W4214519984 cites W2556812031 @default.
- W4214519984 cites W2586842569 @default.
- W4214519984 cites W2597174991 @default.
- W4214519984 cites W2606778500 @default.
- W4214519984 cites W2734591620 @default.
- W4214519984 cites W2763152414 @default.
- W4214519984 cites W2771779479 @default.
- W4214519984 cites W2781313556 @default.
- W4214519984 cites W2790484942 @default.
- W4214519984 cites W2792209082 @default.
- W4214519984 cites W2800004342 @default.
- W4214519984 cites W2801309076 @default.
- W4214519984 cites W2807765114 @default.
- W4214519984 cites W2838505861 @default.
- W4214519984 cites W2895447854 @default.
- W4214519984 cites W2897406763 @default.
- W4214519984 cites W2904128325 @default.
- W4214519984 cites W2906158244 @default.
- W4214519984 cites W2919918774 @default.
- W4214519984 cites W2924020944 @default.
- W4214519984 cites W2938150871 @default.
- W4214519984 cites W2943470918 @default.
- W4214519984 cites W2944019159 @default.
- W4214519984 cites W2949041892 @default.
- W4214519984 cites W2970292207 @default.
- W4214519984 cites W2995039067 @default.
- W4214519984 cites W2999529909 @default.
- W4214519984 cites W2999754551 @default.
- W4214519984 cites W3005196658 @default.
- W4214519984 cites W3008628679 @default.
- W4214519984 cites W3010088053 @default.