FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4214539968> ?p ?o ?g. }

• W4214539968 abstract "Ventricular enlargement measured from T1-weighted magnetic resonance images (MRI) is an indirect measure of Alzheimer disease (AD) progression. Most MRI volumetric studies have assessed structural change derived from 1.5 Tesla MRI. However, 3.0 Tesla scanners are becoming prevalent, and there are few studies assessing potential differences in volumetry between field strengths. More than 25% of ADNI subjects undergo both 1.5 Tesla and 3.0 Tesla MRI. Objectives: to compare the sensitivity of ventricular measures derived from both 1.5 Tesla and 3.0 Tesla MRI in the same subjects. Baseline and 12-month data were obtained from the Alzheimer Disease Neuroimaging Initiative (ADNI), including 42 normal controls (NC), 53 subjects with mild cognitive impairment (MCI) and 20 subjects with AD (mean age =76 years in each group). Baseline and 12-month processed 3D T1-weighted MP-RAGE MRI, and corresponding, demographic measures were collected. Ventricular volume was computed using a semi-automated region-growing algorithm (Cedara Software). Intra-class correlation coefficients (ICCs) were computed to assess differences between 1.5 Tesla and 3.0 Tesla data for cross-sectional and longitudinal measures. A one-way ANOVA was used for group-wise comparisons between NEC, MCI and AD groups for baseline and longitudinal ventricular measures. Ventricular volumes measured from 1.5 Tesla (mean ±SD: NEC=31.5 ±11.2cm3, MCI=51.6 ±23.9cm3, AD= 48.8 ±26.5cm3) were smaller (p<0.001) than ventricular volumes derived from 3.0 Tesla MRI (NEC= 32.8 ±11.2cm3, MCI=53.8 ±24.2cm3, AD=49.8 ±29.4cm3) at baseline (ICC=0.99, p<0.0001). Ventricular enlargement was similar for measures derived from 1.5 Tesla MRI (mean ± SD = 2.6 ± 2.8 cm3) and 3.0 Tesla MRI (mean ± SD = 2.5 ±3.3 cm3) when collapsing across groups (ICC=0.75, p<0.0001). For both field strengths the AD and MCI groups had significantly greater ventricular enlargement after 12 months than the NC group (p<0.01). These data demonstrate similar sensitivities for 1.5 Tesla and 3.0 Tesla derived ventricular measures. Baseline comparisons reveal high reproducibility between field strengths, with a slightly larger ventricular volume for 3.0 Tesla measures. Nevertheless, ventricular enlargement computed from 3.0 and 1.5 Tesla MRI demonstrated comparable group-wise discrimination." @default.
• W4214539968 created "2022-03-02" @default.
• W4214539968 creator A5011579867 @default.
• W4214539968 creator A5023782543 @default.
• W4214539968 creator A5028347310 @default.
• W4214539968 creator A5067317602 @default.
• W4214539968 date "2009-07-01" @default.
• W4214539968 modified "2023-09-27" @default.
• W4214539968 title "P2-013: A direct comparison of ventricular volumes derived from 1.5 Tesla and 3.0 Tesla MRI in 115 ADNI participants" @default.
• W4214539968 doi "https://doi.org/10.1016/j.jalz.2009.04.322" @default.
• W4214539968 hasPublicationYear "2009" @default.
• W4214539968 type Work @default.
• W4214539968 citedByCount "0" @default.
• W4214539968 crossrefType "journal-article" @default.
• W4214539968 hasAuthorship W4214539968A5011579867 @default.
• W4214539968 hasAuthorship W4214539968A5023782543 @default.
• W4214539968 hasAuthorship W4214539968A5028347310 @default.
• W4214539968 hasAuthorship W4214539968A5067317602 @default.
• W4214539968 hasBestOaLocation W42145399681 @default.
• W4214539968 hasConcept C118552586 @default.
• W4214539968 hasConcept C126322002 @default.
• W4214539968 hasConcept C126838900 @default.
• W4214539968 hasConcept C143409427 @default.
• W4214539968 hasConcept C164705383 @default.
• W4214539968 hasConcept C2778373026 @default.
• W4214539968 hasConcept C2779134260 @default.
• W4214539968 hasConcept C2984915365 @default.
• W4214539968 hasConcept C2989005 @default.
• W4214539968 hasConcept C58693492 @default.
• W4214539968 hasConcept C71924100 @default.
• W4214539968 hasConceptScore W4214539968C118552586 @default.
• W4214539968 hasConceptScore W4214539968C126322002 @default.
• W4214539968 hasConceptScore W4214539968C126838900 @default.
• W4214539968 hasConceptScore W4214539968C143409427 @default.
• W4214539968 hasConceptScore W4214539968C164705383 @default.
• W4214539968 hasConceptScore W4214539968C2778373026 @default.
• W4214539968 hasConceptScore W4214539968C2779134260 @default.
• W4214539968 hasConceptScore W4214539968C2984915365 @default.
• W4214539968 hasConceptScore W4214539968C2989005 @default.
• W4214539968 hasConceptScore W4214539968C58693492 @default.
• W4214539968 hasConceptScore W4214539968C71924100 @default.
• W4214539968 hasIssue "4S_Part_9" @default.
• W4214539968 hasLocation W42145399681 @default.
• W4214539968 hasOpenAccess W4214539968 @default.
• W4214539968 hasPrimaryLocation W42145399681 @default.
• W4214539968 hasRelatedWork W104651200 @default.
• W4214539968 hasRelatedWork W1482496268 @default.
• W4214539968 hasRelatedWork W1968631753 @default.
• W4214539968 hasRelatedWork W1986635521 @default.
• W4214539968 hasRelatedWork W2021122701 @default.
• W4214539968 hasRelatedWork W2077875975 @default.
• W4214539968 hasRelatedWork W2538624173 @default.
• W4214539968 hasRelatedWork W2802655428 @default.
• W4214539968 hasRelatedWork W2896427386 @default.
• W4214539968 hasRelatedWork W2936745086 @default.
• W4214539968 hasVolume "5" @default.
• W4214539968 isParatext "false" @default.
• W4214539968 isRetracted "false" @default.
• W4214539968 workType "article" @default.