Matches in SemOpenAlex for { <https://semopenalex.org/work/W4214570632> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4214570632 endingPage "114" @default.
- W4214570632 startingPage "111" @default.
- W4214570632 abstract "The incidence of syphilis among Canadian women of childbearing age has risen dramatically in the past decade, with a resurgence of infants born with congenital syphilis. While guidelines exist to guide maternal infection during pregnancy, there is little evidence available to guide management in situations where the developing fetus is found to be severely affected.Our patient presented in the second trimester of her pregnancy as syphilis contact. Positive serologic tests (venereal disease research laboratory titre of 1:64) and a chancre suggested primary infection. Ultrasound demonstrated a fetus at 19+3 weeks gestation with hydrops fetalis and a markedly abnormal brain. Amniocentesis confirmed congenital syphilis infection on polymerase chain reaction testing. After nine days of intravenous penicillin G, the fetal status had worsened, and the family ultimately chose a medical termination of the pregnancy.Evolving ultrasound technology has allowed us to identify severely affected fetuses, who may historically have been delivered stillborn. Following routine syphiliotherapy with benzathine penicillin, these abnormal ultrasound features may take weeks or months to reverse, which poses a challenge in prognostication and counselling. Case reports data suggests intensive treatment with intravenous penicillin may be effective in severe cases where fetal hydrops is present.This case highlights the potential morbidity of fetal syphilis infection and underscores the paucity of current literature. Information sharing will be essential to build a modern knowledge base on treating this ancient disease." @default.
- W4214570632 created "2022-03-02" @default.
- W4214570632 creator A5008911186 @default.
- W4214570632 creator A5089011345 @default.
- W4214570632 date "2022-02-24" @default.
- W4214570632 modified "2023-09-30" @default.
- W4214570632 title "Exploring management of antenatally diagnosed fetal syphilis infection" @default.
- W4214570632 cites W2014901260 @default.
- W4214570632 cites W2030460870 @default.
- W4214570632 cites W2072441469 @default.
- W4214570632 cites W2153140220 @default.
- W4214570632 cites W2184112488 @default.
- W4214570632 cites W2998705262 @default.
- W4214570632 cites W3015616513 @default.
- W4214570632 cites W3022562207 @default.
- W4214570632 doi "https://doi.org/10.14745/ccdr.v48i23a09" @default.
- W4214570632 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35342369" @default.
- W4214570632 hasPublicationYear "2022" @default.
- W4214570632 type Work @default.
- W4214570632 citedByCount "1" @default.
- W4214570632 countsByYear W42145706322023 @default.
- W4214570632 crossrefType "journal-article" @default.
- W4214570632 hasAuthorship W4214570632A5008911186 @default.
- W4214570632 hasAuthorship W4214570632A5089011345 @default.
- W4214570632 hasBestOaLocation W42145706321 @default.
- W4214570632 hasConcept C126322002 @default.
- W4214570632 hasConcept C131872663 @default.
- W4214570632 hasConcept C172680121 @default.
- W4214570632 hasConcept C174802600 @default.
- W4214570632 hasConcept C187212893 @default.
- W4214570632 hasConcept C203014093 @default.
- W4214570632 hasConcept C2776908936 @default.
- W4214570632 hasConcept C2776983459 @default.
- W4214570632 hasConcept C2777674756 @default.
- W4214570632 hasConcept C2777966818 @default.
- W4214570632 hasConcept C2778258057 @default.
- W4214570632 hasConcept C2779134260 @default.
- W4214570632 hasConcept C2779234561 @default.
- W4214570632 hasConcept C2781232182 @default.
- W4214570632 hasConcept C3013748606 @default.
- W4214570632 hasConcept C501593827 @default.
- W4214570632 hasConcept C54355233 @default.
- W4214570632 hasConcept C71924100 @default.
- W4214570632 hasConcept C86803240 @default.
- W4214570632 hasConcept C89423630 @default.
- W4214570632 hasConceptScore W4214570632C126322002 @default.
- W4214570632 hasConceptScore W4214570632C131872663 @default.
- W4214570632 hasConceptScore W4214570632C172680121 @default.
- W4214570632 hasConceptScore W4214570632C174802600 @default.
- W4214570632 hasConceptScore W4214570632C187212893 @default.
- W4214570632 hasConceptScore W4214570632C203014093 @default.
- W4214570632 hasConceptScore W4214570632C2776908936 @default.
- W4214570632 hasConceptScore W4214570632C2776983459 @default.
- W4214570632 hasConceptScore W4214570632C2777674756 @default.
- W4214570632 hasConceptScore W4214570632C2777966818 @default.
- W4214570632 hasConceptScore W4214570632C2778258057 @default.
- W4214570632 hasConceptScore W4214570632C2779134260 @default.
- W4214570632 hasConceptScore W4214570632C2779234561 @default.
- W4214570632 hasConceptScore W4214570632C2781232182 @default.
- W4214570632 hasConceptScore W4214570632C3013748606 @default.
- W4214570632 hasConceptScore W4214570632C501593827 @default.
- W4214570632 hasConceptScore W4214570632C54355233 @default.
- W4214570632 hasConceptScore W4214570632C71924100 @default.
- W4214570632 hasConceptScore W4214570632C86803240 @default.
- W4214570632 hasConceptScore W4214570632C89423630 @default.
- W4214570632 hasIssue "2-3" @default.
- W4214570632 hasLocation W42145706321 @default.
- W4214570632 hasLocation W42145706322 @default.
- W4214570632 hasLocation W42145706323 @default.
- W4214570632 hasLocation W42145706324 @default.
- W4214570632 hasOpenAccess W4214570632 @default.
- W4214570632 hasPrimaryLocation W42145706321 @default.
- W4214570632 hasRelatedWork W1984075192 @default.
- W4214570632 hasRelatedWork W1990668771 @default.
- W4214570632 hasRelatedWork W2059930430 @default.
- W4214570632 hasRelatedWork W2070859757 @default.
- W4214570632 hasRelatedWork W2087869519 @default.
- W4214570632 hasRelatedWork W2176484957 @default.
- W4214570632 hasRelatedWork W2339007821 @default.
- W4214570632 hasRelatedWork W4214570632 @default.
- W4214570632 hasRelatedWork W4312491910 @default.
- W4214570632 hasRelatedWork W45020768 @default.
- W4214570632 hasVolume "48" @default.
- W4214570632 isParatext "false" @default.
- W4214570632 isRetracted "false" @default.
- W4214570632 workType "article" @default.