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- W4214636699 abstract "Numerous treatments exist for COVID-19, the illness caused by SARS-CoV-2 virus, although most are not well established; among these are several small molecule antiviral agents. Intravenous remdesivir is an established treatment worldwide for inpatients and in some countries is also available for use in non-hospitalised high risk patients to prevent progression to severe disease and hospitalization. Oral molnupiravir and oral nirmatrelvir-ritonavir are also available in several countries to prevent progression to severe disease and hospitalization for high-risk outpatients. Many other antiviral small molecules that may have therapeutic potential are under investigation in clinical trials. This article provides a summary of key molecular targets, pharmacology and preliminary data on the efficacy and safety of small molecule antiviral agents being investigated for the treatment of COVID-19." @default.
- W4214636699 created "2022-03-02" @default.
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- W4214636699 date "2022-02-28" @default.
- W4214636699 modified "2023-10-09" @default.
- W4214636699 title "Emerging small molecule antivirals may fit neatly into COVID-19 treatment" @default.
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- W4214636699 doi "https://doi.org/10.1007/s40267-022-00897-8" @default.
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