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• W4214664151 abstract "Significance The molecular basis of how the BEN domain–containing gene family regulates chromatin function and transcription remains to be elucidated. We report that BEND3 is highly expressed in pluripotent cells and binds to promoters of genes involved in differentiation. BEND3 regulates the expression of differentiation-associated genes by modulating the chromatin architecture at promoters. We propose that transcription repression mediated by BEND3 is essential for normal development and maintenance of pluripotency." @default.
• W4214664151 created "2022-03-02" @default.
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• W4214664151 date "2022-02-25" @default.
• W4214664151 modified "2023-10-18" @default.
• W4214664151 title "BEND3 safeguards pluripotency by repressing differentiation-associated genes" @default.
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• W4214664151 doi "https://doi.org/10.1073/pnas.2107406119" @default.
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