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- W4214666736 endingPage "1161" @default.
- W4214666736 startingPage "1161" @default.
- W4214666736 abstract "The arterial baroreflex is a key autonomic regulator of blood pressure whose dysfunction has been related to several cardiovascular diseases. Changes in blood pressure are sensed by specific mechanosensory proteins, called baroreceptors, particularly located in the outer layer of the carotid sinus and the inner curvature of the aortic arch. The signal is propagated along the afferent nerves to the central nervous system and serves as negative feedback of the heart rate. Despite extensive research, the precise molecular nature of baroreceptors remains elusive. Current knowledge assumes that baroreceptors are ion channels at the nerve endings within the outer layer of the arteries. However, the evidence is based mainly on animal experiments, and the specific types of mechanosensitive receptors responsible for the signal transduction are still unknown. Only a few studies have investigated mechanosensory transmission in the aortic arch. In addition, although aortic dissection, and particularly type A involving the aortic arch, is one of the most life-threatening cardiovascular disorders, there is no knowledge about the impact of aortic dissection on baroreceptor function. In this review, we aim not to highlight the regulation of the heart rate but what mechanical stimuli and what possible ion channels transfer the corresponding signal within the aortic arch, summarizing and updating the current knowledge about baroreceptors, specifically in the aortic arch, and the impact of aortic pathologies on their function." @default.
- W4214666736 created "2022-03-02" @default.
- W4214666736 creator A5020472674 @default.
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- W4214666736 creator A5083203128 @default.
- W4214666736 date "2022-02-22" @default.
- W4214666736 modified "2023-09-26" @default.
- W4214666736 title "Baroreceptors in the Aortic Arch and Their Potential Role in Aortic Dissection and Aneurysms" @default.
- W4214666736 cites W146513063 @default.
- W4214666736 cites W148882110 @default.
- W4214666736 cites W1525997168 @default.
- W4214666736 cites W1547594413 @default.
- W4214666736 cites W1565618263 @default.
- W4214666736 cites W1820962178 @default.
- W4214666736 cites W1863048352 @default.
- W4214666736 cites W1937806449 @default.
- W4214666736 cites W1969203315 @default.
- W4214666736 cites W1970402393 @default.
- W4214666736 cites W1975461211 @default.
- W4214666736 cites W1977013066 @default.
- W4214666736 cites W1978533452 @default.
- W4214666736 cites W1990711883 @default.
- W4214666736 cites W1994929421 @default.
- W4214666736 cites W1995481189 @default.
- W4214666736 cites W1997080801 @default.
- W4214666736 cites W1998106094 @default.
- W4214666736 cites W1999720993 @default.
- W4214666736 cites W2004074414 @default.
- W4214666736 cites W2007699116 @default.
- W4214666736 cites W2013354919 @default.
- W4214666736 cites W2015902564 @default.
- W4214666736 cites W2034093166 @default.
- W4214666736 cites W2035681742 @default.
- W4214666736 cites W2040664792 @default.
- W4214666736 cites W2044773759 @default.
- W4214666736 cites W2050575405 @default.
- W4214666736 cites W2052544958 @default.
- W4214666736 cites W2056677141 @default.
- W4214666736 cites W2056941285 @default.
- W4214666736 cites W2063346192 @default.
- W4214666736 cites W2067079444 @default.
- W4214666736 cites W2078749006 @default.
- W4214666736 cites W2080695099 @default.
- W4214666736 cites W2083824794 @default.
- W4214666736 cites W2086171798 @default.
- W4214666736 cites W2092684906 @default.
- W4214666736 cites W2101718304 @default.
- W4214666736 cites W2104659034 @default.
- W4214666736 cites W2104984002 @default.
- W4214666736 cites W2105365877 @default.
- W4214666736 cites W2110642841 @default.
- W4214666736 cites W2114604004 @default.
- W4214666736 cites W2116320226 @default.
- W4214666736 cites W2118230456 @default.
- W4214666736 cites W2122253638 @default.
- W4214666736 cites W2124899167 @default.
- W4214666736 cites W2128324733 @default.
- W4214666736 cites W2131511103 @default.
- W4214666736 cites W2135064193 @default.
- W4214666736 cites W2137423684 @default.
- W4214666736 cites W2139176711 @default.
- W4214666736 cites W2140281925 @default.
- W4214666736 cites W2145576288 @default.
- W4214666736 cites W2157174760 @default.
- W4214666736 cites W2161722088 @default.
- W4214666736 cites W2164123970 @default.
- W4214666736 cites W2168890553 @default.
- W4214666736 cites W2171999802 @default.
- W4214666736 cites W2193068214 @default.
- W4214666736 cites W2227999806 @default.
- W4214666736 cites W2270931098 @default.
- W4214666736 cites W2342686466 @default.
- W4214666736 cites W2354944428 @default.
- W4214666736 cites W2410823596 @default.
- W4214666736 cites W2411986643 @default.
- W4214666736 cites W2413875757 @default.
- W4214666736 cites W2414869539 @default.
- W4214666736 cites W2470912538 @default.
- W4214666736 cites W2513576822 @default.
- W4214666736 cites W2566932600 @default.
- W4214666736 cites W2805692005 @default.
- W4214666736 cites W2889169994 @default.
- W4214666736 cites W2889838671 @default.
- W4214666736 cites W2898266525 @default.
- W4214666736 cites W2905098405 @default.
- W4214666736 cites W2936783046 @default.
- W4214666736 cites W2967805680 @default.
- W4214666736 cites W3040333459 @default.
- W4214666736 cites W3199382522 @default.
- W4214666736 cites W4210431459 @default.
- W4214666736 cites W4210581702 @default.
- W4214666736 cites W74876346 @default.
- W4214666736 doi "https://doi.org/10.3390/jcm11051161" @default.
- W4214666736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35268252" @default.
- W4214666736 hasPublicationYear "2022" @default.