Matches in SemOpenAlex for { <https://semopenalex.org/work/W4214670668> ?p ?o ?g. }
- W4214670668 abstract "To assess the effect of antiandrogenic pretreatment using combined oral contraceptives (COCs) before ovulation induction in infertile patients with polycystic ovary syndrome (PCOS) with hyperandrogenism.Prospective, randomized open-labeled cohort study.Multicenter.PCOS patients with hyperandrogenism and requiring infertility treatments.Randomization to direct ovulation induction of letrozole (letrozole group) or ethinylestradiol/cyproterone acetate (EE/CPA) for 3 months and subsequent letrozole-induced ovulation (EE/CPA+ letrozole group). The maximum number of ovulation induction cycle was three to four.Ovulation rate, conception rate, ongoing pregnancy rate, and live birth rate were the main outcomes of the study.There were no significant differences in the cumulative ovulation, conception, ongoing pregnancy, and live birth rates between the letrozole and EE/CPA+ letrozole groups (cumulative ovulation: 206/254 [81.10%] vs. 169/205 [82.44%], risk ratio [RR]= 1.09 [0.68,1.76], P=0.713; conception: 44/90 [48.89%] vs. 42/76 [55.26%], RR= 1.29 [0.70,2.38], P=0.413; ongoing pregnancy: 33/90 [36.67%] vs. 33/76 [43.42%], RR=1.33 [0.71,2.47], P=0.376; and live birth: 32/90 [35.56%] vs. 31/76 [40.79%], RR=1.25 [0.67, 2.34], P=0.489).The results of this study showed that COC pretreatment was not superior to direct letrozole-induced ovulation therapy in improving ovulation and pregnancy results in women with PCOS. There is no benefit to perform antiandrogenic therapy before ovulation induction in patients with PCOS in clinical practice.www.clinicaltrials.gov, identifier ChiCTR1900022839." @default.
- W4214670668 created "2022-03-02" @default.
- W4214670668 creator A5009674897 @default.
- W4214670668 creator A5010360573 @default.
- W4214670668 creator A5012485738 @default.
- W4214670668 creator A5015478319 @default.
- W4214670668 creator A5034251280 @default.
- W4214670668 creator A5054551595 @default.
- W4214670668 creator A5059958350 @default.
- W4214670668 creator A5069112627 @default.
- W4214670668 creator A5084358534 @default.
- W4214670668 date "2022-02-24" @default.
- W4214670668 modified "2023-10-18" @default.
- W4214670668 title "A Randomized Cohort Study: Is It Worth the Time to Receive Antiandrogenic Pretreatment Before Ovulation Induction for Women With Polycystic Ovary Syndrome?" @default.
- W4214670668 cites W1836408129 @default.
- W4214670668 cites W1973385303 @default.
- W4214670668 cites W1982923059 @default.
- W4214670668 cites W2022195233 @default.
- W4214670668 cites W2032972327 @default.
- W4214670668 cites W2035217519 @default.
- W4214670668 cites W2052761879 @default.
- W4214670668 cites W2091512839 @default.
- W4214670668 cites W2100306033 @default.
- W4214670668 cites W2122612739 @default.
- W4214670668 cites W2133883611 @default.
- W4214670668 cites W2137118345 @default.
- W4214670668 cites W2142157239 @default.
- W4214670668 cites W2152740900 @default.
- W4214670668 cites W2159902645 @default.
- W4214670668 cites W2169949390 @default.
- W4214670668 cites W2369321124 @default.
- W4214670668 cites W2395505927 @default.
- W4214670668 cites W2464105488 @default.
- W4214670668 cites W2520432709 @default.
- W4214670668 cites W2522503768 @default.
- W4214670668 cites W2547249799 @default.
- W4214670668 cites W2548567961 @default.
- W4214670668 cites W2613790258 @default.
- W4214670668 cites W2726145925 @default.
- W4214670668 cites W2751479028 @default.
- W4214670668 cites W2789960609 @default.
- W4214670668 cites W2808702457 @default.
- W4214670668 cites W2854044000 @default.
- W4214670668 cites W2884536266 @default.
- W4214670668 cites W2889621887 @default.
- W4214670668 cites W2980249081 @default.
- W4214670668 cites W2981472135 @default.
- W4214670668 cites W2987017313 @default.
- W4214670668 cites W3014818879 @default.
- W4214670668 cites W3085884366 @default.
- W4214670668 cites W3089639006 @default.
- W4214670668 cites W3104254993 @default.
- W4214670668 cites W3143698580 @default.
- W4214670668 cites W4244088697 @default.
- W4214670668 cites W4251646064 @default.
- W4214670668 cites W4252430351 @default.
- W4214670668 doi "https://doi.org/10.3389/fendo.2022.813188" @default.
- W4214670668 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35282449" @default.
- W4214670668 hasPublicationYear "2022" @default.
- W4214670668 type Work @default.
- W4214670668 citedByCount "2" @default.
- W4214670668 countsByYear W42146706682023 @default.
- W4214670668 crossrefType "journal-article" @default.
- W4214670668 hasAuthorship W4214670668A5009674897 @default.
- W4214670668 hasAuthorship W4214670668A5010360573 @default.
- W4214670668 hasAuthorship W4214670668A5012485738 @default.
- W4214670668 hasAuthorship W4214670668A5015478319 @default.
- W4214670668 hasAuthorship W4214670668A5034251280 @default.
- W4214670668 hasAuthorship W4214670668A5054551595 @default.
- W4214670668 hasAuthorship W4214670668A5059958350 @default.
- W4214670668 hasAuthorship W4214670668A5069112627 @default.
- W4214670668 hasAuthorship W4214670668A5084358534 @default.
- W4214670668 hasBestOaLocation W42146706681 @default.
- W4214670668 hasConcept C121608353 @default.
- W4214670668 hasConcept C126322002 @default.
- W4214670668 hasConcept C131872663 @default.
- W4214670668 hasConcept C134018914 @default.
- W4214670668 hasConcept C2776537878 @default.
- W4214670668 hasConcept C2777176818 @default.
- W4214670668 hasConcept C2777391703 @default.
- W4214670668 hasConcept C2777702977 @default.
- W4214670668 hasConcept C2778279030 @default.
- W4214670668 hasConcept C2778812593 @default.
- W4214670668 hasConcept C2779234561 @default.
- W4214670668 hasConcept C2779306644 @default.
- W4214670668 hasConcept C2780186808 @default.
- W4214670668 hasConcept C2781230225 @default.
- W4214670668 hasConcept C29456083 @default.
- W4214670668 hasConcept C3018442814 @default.
- W4214670668 hasConcept C530470458 @default.
- W4214670668 hasConcept C54355233 @default.
- W4214670668 hasConcept C71315377 @default.
- W4214670668 hasConcept C71924100 @default.
- W4214670668 hasConcept C86803240 @default.
- W4214670668 hasConceptScore W4214670668C121608353 @default.
- W4214670668 hasConceptScore W4214670668C126322002 @default.
- W4214670668 hasConceptScore W4214670668C131872663 @default.
- W4214670668 hasConceptScore W4214670668C134018914 @default.
- W4214670668 hasConceptScore W4214670668C2776537878 @default.
- W4214670668 hasConceptScore W4214670668C2777176818 @default.