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- W4214683445 endingPage "899" @default.
- W4214683445 startingPage "899" @default.
- W4214683445 abstract "In recent years, the number of people needing bone replacements for the treatment of defects caused by chronic diseases or accidents has continuously increased. To solve these problems, tissue engineering has gained significant attention in the biomedical field, by focusing on the development of suitable materials that improve osseointegration and biologic activity. In this direction, the development of an ideal material that provides good osseointegration, increased antimicrobial activity and preserves good mechanical properties has been the main challenge. Currently, bone tissue engineering focuses on the development of materials with tailorable properties, by combining polymers and ceramics to meet the necessary complex requirements. This study presents the main polymers applied in tissue engineering, considering their advantages and drawbacks. Considering the potential disadvantages of polymers, improving the applicability of the material and the combination with a ceramic material is the optimum pathway to increase the mechanical stability and mineralization process. Thus, ceramic materials obtained from natural sources (e.g., hydroxyapatite) are preferred to improve bioactivity, due to their similarity to the native hydroxyapatite found in the composition of human bone." @default.
- W4214683445 created "2022-03-02" @default.
- W4214683445 creator A5028412434 @default.
- W4214683445 creator A5034236725 @default.
- W4214683445 creator A5066717310 @default.
- W4214683445 creator A5090824290 @default.
- W4214683445 date "2022-02-24" @default.
- W4214683445 modified "2023-10-18" @default.
- W4214683445 title "Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering" @default.
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