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- W4214684313 abstract "Abstract Objective: The overall and genotype specific prevalence of HPV infection was assessed among healthy Chinese women and the temporal and geographical prevalence was also estimated. Methods: We selected healthy population studies on HPV prevalence published between Jan 1995 and Dec 2018. It was estimated by meta-analysis based on regions, cytological and histological characters, ages. Results: The overall HPV prevalence in 856,535 healthy women was estimated to be 14.3 % (95%CI: 13.1, 15.5). The prevalence of high-risk and low-risk types of HPV were 11.3% and 2.7 %. The most common types of HPV were HPV 16 (2.6%), 52(2.4%), 58(1.7%), 18(0.9%), 33(0.8%). The prevalence of different genotypes of HPV varied in seven China regions. The Central China had the highest in overall HPV prevalence, high and low-risk HPV prevalence, which reported as19.8%, 15.1% and 4.8%. HPV16(from1.8% to 5.3%) was the most common type in other regions except for South China and East China, where HPV52(from 1.0% to 2.8%) was more common than other types. The HPV infection lead to cervical cancer diagnosis by cytology and histology were 90.1% and 91.5%. HPV16 and HPV 18 were common types in cervical cancer diagnosed by cytology and histology. Overall HPV prevalence increased significantly from 8.2% to 16.5% in studies published from 2006 to 2018. Conclusion: HPV 16, 58, 52, 18 and 33 were the most common types in healthy women in mainland China. The prevalence of different HPV genotypes was varied in various age groups and regions time." @default.
- W4214684313 created "2022-03-02" @default.
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- W4214684313 date "2019-06-12" @default.
- W4214684313 modified "2023-09-27" @default.
- W4214684313 title "The prevalence of cervical HPV infection and genotype distribution in 856,535 healthy Chinese women: a systemic review" @default.
- W4214684313 doi "https://doi.org/10.21203/rs.2.10228/v1" @default.
- W4214684313 hasPublicationYear "2019" @default.
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